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Proper Citation: RRID:BCBC_181
Description: Homozygous phenotype: Postnatal lethal due to neonatal diabetes Pancreas--5% insulin production, no islet formation Gut--no CCK or secretin production Inner ear defects resulting in deafness--no cochlear ganglia and poor vestibular ganglia formation Cerebellar defect resulting in ataxia-- >90% depletion of cerebellar granule cells Hippocampal defects--no dentate gyrus.
Species: Mus musculus
Notes: Homozygous phenotype: Postnatal lethal due to neonatal diabetes Pancreas--5% insulin production, no islet formation Gut--no CCK or secretin production Inner ear defects resulting in deafness--no cochlear ganglia and poor vestibular ganglia formation Cerebellar defect resulting in ataxia-- >90% depletion of cerebellar granule cells Hippocampal defects--no dentate gyrus.
Phenotype: Diabetes mellitus
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No rating or validation information has been found for NeuroD/lacZ Knock-In (BX129-Neurod1tmAK71(lacZ)Jle/Mmcd).
No alerts have been found for NeuroD/lacZ Knock-In (BX129-Neurod1tmAK71(lacZ)Jle/Mmcd).
Source: Integrated Animals
Source Database: BCBC, Beta Cell Biology Consortium
