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This service exclusively searches for literature that cites resources. Please be aware that the total number of searchable documents is limited to those containing RRIDs and does not include all open-access literature.

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On page 1 showing 1 ~ 4 papers out of 4 papers

Multiancestral polygenic risk score for pediatric asthma.

  • Bahram Namjou‎ et al.
  • The Journal of allergy and clinical immunology‎
  • 2022‎

Asthma is the most common chronic condition in children and the third leading cause of hospitalization in pediatrics. The genome-wide association study catalog reports 140 studies with genome-wide significance. A polygenic risk score (PRS) with predictive value across ancestries has not been evaluated for this important trait.


A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci.

  • Xiao Chang‎ et al.
  • The Journal of allergy and clinical immunology‎
  • 2022‎

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus marked by eosinophilic infiltration. Cumulative evidence indicates that the risk of EoE involves the complex interplay of both genetic and environmental factors. Because only a few genetic loci have been identified in EoE, the genetic underpinning of EoE remains largely elusive.


Unsupervised modeling and genome-wide association identify novel features of allergic march trajectories.

  • Stanislaw J Gabryszewski‎ et al.
  • The Journal of allergy and clinical immunology‎
  • 2021‎

The allergic march refers to the natural history of allergic conditions during infancy and childhood. However, population-level disease incidence patterns do not necessarily reflect the development of allergic disease in individuals. A better understanding of the factors that predispose to different allergic trajectories is needed.


Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder.

  • Michael D Keller‎ et al.
  • The Journal of allergy and clinical immunology‎
  • 2016‎

Genome-wide association studies have shown a pattern of rare copy number variations and single nucleotide polymorphisms in patients with common variable immunodeficiency disorder (CVID), which was recognizable by a support vector machine (SVM) algorithm. However, rare monogenic causes of CVID might lack such a genetic fingerprint.


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