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Neostriatum direct pathway spiny neuron
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The principal projection neuron of the caudate and putamen.
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NLX:149135
|
term
|
ILX:0107404
|
535.9772
|
Neuron, Nervous system cell, Cell, Anatomical entity, Independent continuant, Continuant |
MSN, Medium spiny neuron, Neostriatal spiny neuron, Medium-sized spiny neuron, Striatal spiny neuron, striatal direct pathway spiny neuron, direct pathway medium spiny neuron, direct pathway medium-sized spiny neuron, dMSN, neostriatial direct pathway spiny neuron |
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Neostriatum indirect pathway spiny neuron
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The principal projection neuron of the caudate and putamen.
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NLX:149136
|
term
|
ILX:0107405
|
527.3705
|
Neuron, Nervous system cell, Cell, Anatomical entity, Independent continuant, Continuant |
MSN, Medium spiny neuron, Neostriatal spiny neuron, Medium-sized spiny neuron, Striatal spiny neuron, indirect pathway medium-sized spiny neuron, iMSN, striatal indirect pathway spiny neuron, neostriatial indirect pathway spiny neuron, indirect pathway medium spiny neuron |
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Medium soma
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A medium sized soma, defined relative to the brain.
|
NLX:45865
|
term
|
ILX:0106731
|
286.37308
|
Soma Size, Soma Quality, Morphological Quality, Quality, Specifically dependent continuant, Dependent continuant, Continuant |
|
|
Neostriatum cholinergic cell
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Large cholinergic interneuron in the caudate nucleus and putamen, extensive axon collaterals terminate on striatal medium spiny neurons
|
SAO:1866881837
|
term
|
ILX:0107403
|
278.68573
|
Neuron, Nervous system cell, Cell, Anatomical entity, Independent continuant, Continuant |
Giant cholinergic interneuron, Striatal cholinergic interneuron, large striatal aspiny neuron, cholinergic striatal neuron, Neostriatum cholinergic interneuron, Neostriatum giant cell of Kolliker, Neostriatal cholinergic interneuron, neostriatum cholinergic cell, neostriatial cholinergic interneuron, CIN |
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Spiny high density
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Characterized by a high density of dendritic spines, of sufficient density to give the dendrite a fuzzy coated appearance in light microscopic preparations
|
NLX:146270
|
term
|
ILX:0110981
|
196.26848
|
Quality, Specifically dependent continuant, Dependent continuant, Continuant |
spiny |
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Principal neuron role
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Neuron whose axon projects out of the region in which the cell soma lies to carry information to another region
|
ILX:0109349
|
term
|
ILX:0109349
|
157.74226
|
Projection role of nerve cell, Functional role of nerve cell, Functional role of cell, Cell role, Role, Realizable entity, Specifically dependent continuant, Dependent continuant, Continuant |
Projection neuron role, Principal neuron |
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Axon myelination
|
|
ILX:0112766
|
annotation
|
ILX:0112766
|
19.425396
|
|
|
|
Cell soma size
|
|
ILX:0112777
|
relationship
|
ILX:0112777
|
18.10753
|
|
|
|
Nucleus accumbens
|
A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen. (caudoputamen in rodent) and continuous with these structures. There is no distinct boundary between the nucleus accumbens and the caudate/putamen, but in rodents, it can be identified by its lack of traversing fiber bundles in comparison to the dorsal striatum. Its principle neuron is the medium spiny neuron. Together with the neostriatum (caudate nucleus and putamen), the nucleus accumbens forms the striatum.
|
UBERON:0001882
|
term
|
ILX:0107736
|
16.41418
|
Nucleus of CNS, Regional part of brain, Regional part of nervous system, Regional part of body system, Anatomical entity, Independent continuant, Continuant |
Acb, nucleus accumbens septi, accumbens nucleus, colliculus of caudate nucleus, colliculus nuclei caudati |
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Spine density on dendrites
|
|
ILX:0112798
|
relationship
|
ILX:0112798
|
16.028872
|
|
|
|
Molecular constituents
|
|
ILX:0112790
|
relationship
|
ILX:0112790
|
13.582609
|
|
|
|
Neurotransmitter receptors
|
|
ILX:0112791
|
relationship
|
ILX:0112791
|
13.376527
|
|
|
|
AMPA-type glutamate-gated cationic channel
|
Cell surface proteins that bind glutamate and directly gate ion channels in cell membranes. AMPA receptors were originally discriminated from other glutamate receptors by their affinity for the agonist AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). They are probably the most common mediators of fast excitatory synaptic transmission in the central nervous system. Several subtypes have been cloned, and for some types the traditional distinction from kainate receptors may not apply (MSH).
|
NIFEXT:5251
|
term
|
ILX:0100559
|
12.916642
|
Glutamate-gated cationic channel, Tetrameric ion channel, Multimeric ion channel, Macromolecular complex, Biomolecule, Anatomical entity, Independent continuant, Continuant |
AMPA receptor, AMPA, ionotropic glutamate AMPA receptor, quisqualate receptor, AMPA-type glutamate-gated cationic channel, AMPAR, ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor, ionotropic AMPA receptor |
|
Location of local axon arborization
|
|
ILX:0112787
|
relationship
|
ILX:0112787
|
11.555176
|
|
|
|
Located in
|
|
ILX:0112786
|
relationship
|
ILX:0112786
|
10.174033
|
|
|
|
Cell soma shape
|
|
ILX:0112775
|
relationship
|
ILX:0112775
|
8.229895
|
|
|