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130 Results - per page
| Name |
Description |
Preferred ID |
Type |
ID |
Score | ||
|---|---|---|---|---|---|---|---|
| Acetylcholine Receptor | Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology (MSH). | SAO:1700719022 | term | ILX:0100242 | 23367.799 | Neurotransmitter Receptor, Receptor role, Molecule role, Role, Realizable entity, Specifically dependent continuant, Dependent continuant, Continuant | cholinergic receptor |
| Acetylcholine (muscarinic) receptor | One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3....) that are characterized by their cellular actions, pharmacology, and molecular biology.Year introduced: 1984(1977) - adapted from MeSH | SAO:2062447305 | term | ILX:0100241 | 405.03098 | G-protein coupled receptor, Protein, Molecular entity, Material entity, Independent continuant, Continuant | mAChR, Muscarinic ACh receptor, Muscarinic AChR |
| acetylcholine receptor kinase | MESH:M0107415 | term | ILX:0567327 | 396.5801 | |||
| Nicotinic Acetylcholine Receptor | Classic ligand-gated ion channel receptor type, where binding of ligand (acetylcholine) to transmembrane protein oligomer causes channel to open, permitting ion (sodium and potassium) flux and depolarization (CSP). | SAO:1767745398 | term | ILX:0107579 | 391.96964 | Neurotransmitter Receptor, Receptor role, Molecule role, Role, Realizable entity, Specifically dependent continuant, Dependent continuant, Continuant | Nicotinic cholinergic receptor |
| polyalanyl acetylcholine receptor | MESH:M0087256 | term | ILX:0567334 | 385.05942 | |||
| Alpha 3 Acetylcholine Receptor | Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot). | SAO:99825125 | term | ILX:0100486 | 376.7647 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | Neuronal Acetylcholine Receptor Subunit Alpha-3, CHRNA3, NACHRA3, Cholinergic receptor, nicotinic |
| Alpha 7 Acetylcholine Receptor | This receptor it a protein that is a translation product of the CHRNA7 gene or a 1:1 ortholog thereof. NACHRA7 is a type of nicotinic acetylcholine receptor, consisting entirely of α7 subunits. As with other nicotinic acetylcholine receptors, functional α7 receptors are pentameric [i.e., (α7)5 stoichiometry]. It is located in the brain, where activation yields post- and presynaptic excitation, mainly by increased Ca2+ permeability. (Definition provided by PRotein Ontology and Wikipedia). | SAO:138926812 | term | ILX:0100487 | 376.7647 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | NACHRA7, Acra7, Acetylcholine Receptor Alpha 7, CHRNA7, Cholinergic receptor nicotinic alpha 7, Neuronal acetylcholine receptor subunit alpha-7 |
| alpha7 Nicotinic Acetylcholine Receptor | A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric ñ7 subunits expressed in the CNS, autonomic nervous system, vascular system, lymphocytes and spleen. | MESH:M0089028 | term | ILX:0491154 | 367.5251 | ||
| alpha6beta2 nicotinic acetylcholine receptor | MESH:M0559143 | term | ILX:0601037 | 366.4009 | |||
| acetylcholine receptor gamma, mouse | MESH:M0559177 | term | ILX:0600648 | 350.4107 | |||
| nicotinic acetylcholine receptor alpha4 subunit | MESH:M0275903 | term | ILX:0394603 | 338.01044 | |||
| alpha6beta2 nicotinic acetylcholine receptor, mouse | MESH:M0548298 | term | ILX:0680617 | 338.01044 | |||
| nicotinic acetylcholine receptor delta, zebrafish | MESH:M0499413 | term | ILX:0544699 | 336.23975 | |||
| alpha6beta2 nicotinic acetylcholine receptor, rat | MESH:M0506850 | term | ILX:0680623 | 331.41833 | |||
| Neuronal acetylcholine receptor subunit alpha-6 | A protein that is a translation product of the CHRNA6 gene or a 1:1 ortholog thereof. The ?6 subunit found in certain types of nicotinic acetylcholine receptors found primarily in the brain. Neural nicotinic acetylcholine receptors containing ?6 subunits are expressed on dopamine-releasing neurons in the midbrain, and dopamine release following activation of these neurons is thought to be involved in the addictive properties of nicotine. Due to their selective localisation on dopaminergic neurons, ?6-containing nACh receptors have also been suggested as a possible therapeutic target for the treatment of Parkinson's disease.(Adapted from PRotein Ontology and Wikipedia). | ILX:0107506 | term | ILX:0107506 | 327.26398 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | NACHRA6, Cholinergic receptor, nicotinic, alpha 6, Nica6, CHRNA6, NACHR alpha 6 |
| Neuronal acetylcholine receptor subunit alpha-8 | This receptor it a protein that is a translation product of the CHRNA8 gene or a 1:1 ortholog thereof. NACHRA8 is a type of nicotinic acetylcholine receptor, consisting entirely of α8 subunits. This is the a type of neuronal-type II receptor subtype and these receptors are most present with in the brain. | ILX:0107507 | term | ILX:0107507 | 327.26398 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | NACHRA8, Acra8, Acetylcholine Receptor Alpha 8, CHRNA, Cholinergic receptor nicotinic alpha 8 |
| Neuronal acetylcholine receptor subunit alpha-9 | A protein that is a translation product of the CHRNA9 gene or a 1:1 ortholog thereof. This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells. (Adapted from PRotein Ontology and Entrez Gene). | ILX:0107508 | term | ILX:0107508 | 327.26398 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | NACHRA9, nicotinic acetylcholine receptor subunit alpha 9, NACHR alpha 9, CHRNA9, Cholinergic receptor, nicotinic, alpha 9, HSA243342, MGC142109 |
| Neuronal acetylcholine receptor subunit alpha-4 | A protein that is a translation product of the CHRNA4 gene or a 1:1 ortholog thereof. | ILX:0107505 | term | ILX:0107505 | 327.26398 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | NACRA4, CHRNA4, EBN, BFNC, EBN1, NACHR, NACHRA4, FLJ95812, cholinergic receptor nicotinic alpha 4, Nicotinic alpha 4 receptor |
| Neuronal acetylcholine receptor subunit beta-4 | A protein that is a translation product of the CHRNB4 gene or a 1:1 ortholog thereof. The neuronal acetylcholine receptor is composed of an alpha and a beta subunit. Neuronal acetylcholine receptor beta-4 subunit can be combined with alpha- 2, alpha-3 or alpha-4 to give rise to functional receptor complexes. (Adapted from UniProtKB/Swiss-Prot) | ILX:0107512 | term | ILX:0107512 | 323.77393 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | NACRB4, Acrb4, Neuronal Acetylcholine Receptor Subunit Beta-4, CHRNB4, Cholinergic receptor, nicotinic |
| Neuronal acetylcholine receptor subunit beta-3 | A protein that is a translation product of the CHRNB3 gene or a 1:1 ortholog thereof. (Adapted from PRotein Ontology). | ILX:0107511 | term | ILX:0107511 | 323.21887 | Protein, Molecular entity, Material entity, Independent continuant, Continuant | NACHRB3, Cholinergic receptor, nicotinic, beta 3, CHRNB3 |
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