Drug of abuse role
Description: A drug that is taken for nonmedicinal reasons (usually for mind-altering effects) (Wordnet)
Preferred ID: ILX:0103578 Type: term ID# ILX:0103578 Score: 23486.078
Has role Relationship
Description:
Preferred ID: ILX:0112784 Type: relationship ID# ILX:0112784 Score: 233.37622
Club drug
Description: A drug of abuse that is used by teenagers and young adults at bars, nightclubs, concerts, and parties. Club drugs include GHB, Rohypnol®, ketamine, and others. [MDMA (Ecstasy), Methamphetamine, and LSD (Acid), are considered club drugs and are covered in their individual drug summaries. - adapted from NIDA
Preferred ID: NLX:89990 Type: term ID# ILX:0102280 Score: 205.37607
ysuaa1 (Young Adult Version of the Diagnostic Interview Scale for Children) CDE
Description: Abuse. Other drug abuse/dependence. Failure to fulfill major role obligations
Preferred ID: NDA.CDE:2083078 Type: cde ID# CDE:0316667 Score: 59.963287
Methaqualone hydrochloride
Description:
Preferred ID: ILX:0106855 Type: term ID# ILX:0106855 Score: 22.80828
Dextroamphetamine sulfate
Description: An amphetamine sulfate that has formula C18H28N2O4S.
Preferred ID: CHEBI:51064 Type: term ID# ILX:0103180 Score: 22.32671
Flunitrazepam
Description: A benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug. (PubChem) Pharmacology: Flunitrazepam is a powerful hypnotic drug that is a benzodiazepine derivative. It has powerful hypnotic, sedative, anxiolytic, and skeletal muscle relaxant properties. The drug is sometimes used as a date rape drug. In the United States, the drug has not been approved by the Food and Drug Administration for medical use, and is considered to be an illegal drug. It has however been approved in the United Kingdom and other countries. Mechanism of action: Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell. Drug type: Approved. Illicit. Small Molecule. Drug category: Anti-anxiety Agents. Benzodiazepines. GABA Modulators. Hypnotics and Sedatives
Preferred ID: ILX:0104310 Type: term ID# ILX:0104310 Score: 22.32671
Cyclohexyl nitrite
Description: An alkyl nitrite made from cyclohexanol. It acts as an antianginal. (Wikipedia)
Preferred ID: ILX:0102733 Type: term ID# ILX:0102733 Score: 22.262554
Alkyl nitrite
Description: With a long history of safe medical use in treating angina, as well as an antidote to cyanide poisoning, several alkyl nitrites which are used in over-the-counter products, such as air fresheners and video head cleaners, are often inhaled with the goal of enhancing sexual pleasure and have also been part of the club culture from the 1970s disco scene to the 1980s and 1990s rave scene. (Adapted from Wikipedia)
Preferred ID: ILX:0100472 Type: term ID# ILX:0100472 Score: 21.561737
Opium
Description:
Preferred ID: ILX:0108063 Type: term ID# ILX:0108063 Score: 21.169739
Butane
Description: An alkane that has formula C4H10.
Preferred ID: CHEBI:37808 Type: term ID# ILX:0101507 Score: 21.169739
Biphetamine
Description:
Preferred ID: ILX:0101311 Type: term ID# ILX:0101311 Score: 21.079725
Heroin
Description: A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed)
Preferred ID: CHEBI:27808 Type: term ID# ILX:0104967 Score: 20.82791
Methamphetamine hydrochloride
Description:
Preferred ID: CHEBI:35340 Type: term ID# ILX:0106851 Score: 20.775839
Mescaline
Description: A phenethylamine alkaloid that has formula C11H17NO3.
Preferred ID: CHEBI:28346 Type: term ID# ILX:0106811 Score: 20.566418
Nitrous oxide
Description: A nitrogen oxide that has formula N2O.
Preferred ID: CHEBI:17045 Type: term ID# ILX:0107616 Score: 20.328201
Isobutyl nitrite
Description: A nitrite ester that has formula C4H9NO2.
Preferred ID: CHEBI:46643 Type: term ID# ILX:0105733 Score: 20.328201
Anabolic steroid
Description:
Preferred ID: CHEBI:50786 Type: term ID# ILX:0100592 Score: 19.85191
Benzedrine
Description: The trade name of the racemic mixture of amphetamine (dl-amphetamine) and marketed in the form of inhalers. Benzedrine was used to enlarge nasal and bronchial passages and it is closely related to other stimulants, such as dextroamphetamine (d-amphetamine) and methamphetamine. While the drug was initially used for medical purposes, as a bronchodilator, early users of the Benzedrine inhaler discovered that it had a euphoric stimulant effect, resulting in it being one of the earliest synthetic stimulants to be widely used for recreational (i.e., non-medical) purposes.(Adapted from Wikipedia)
Preferred ID: ILX:0101217 Type: term ID# ILX:0101217 Score: 19.389435
Amyl Nitrite
Description: Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning. Like other alkyl nitrites, amyl nitrite is bioactive in mammals, being a vasodilator which is the basis of its use as a prescription medicine. As an inhalant, it also has psychoactive effect which has led to illegal drug use. Pharmacology: Amyl nitrite, in common with other alkyl nitrites, is a potent vasodilator. It expands blood vessels, resulting in lowering of the blood pressure. Alkyl nitrite functions as a source of nitric oxide, which signals for relaxation of the involuntary muscles. Physical effects include decrease in blood pressure, headache, flushing of the face, increased heart rate, dizziness, and relaxation of involuntary muscles, especially the blood vessel walls and the anal sphincter. There are no withdrawal symptoms. Mechanism of action: Amyl nitrite's antianginal action is thought to be the result of a reduction in systemic and pulmonary arterial pressure (afterload) and decreased cardiac output because of peripheral vasodilation, rather than coronary artery dilation. As an antidote (to cyanide poisoning), amyl nitrite promotes formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin. Drug type: Approved. Small Molecule. Drug category: Vasodilator Agents
Preferred ID: CHEBI:2691 Type: term ID# ILX:0100583 Score: 19.241325
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