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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Results ID Issuer Name of healthcare provider which issued the results ID. ILX:0109983 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retapamulin Retapamulin is a topical antibiotic developed by GlaxoSmithKline. It was approved by the United States Food and Drug Administration in April 2007 for the treatment of bacterial skin infections such as impetigo. It is marketed as an ointment under the name brand Altabax. It works by inhibiting the bacterial 50S ribosomal unit by binding to the 23S RNA. This prevents peptide synthesis. Pharmacology: Retapamulin is a bacterial protein synthesis inhibitor belonging to a class of compounds called pleuromutilins. These compounds act by inhibiting the initiation of protein synthesis at the level of bacterial 50S ribosome. Mechanism of action: Retapamulin is a bacterial protein synthesis inhibitor belonging to a class of compounds called pleuromutilins. These compounds act by inhibiting the initiation of protein synthesis at the level of bacterial 50S ribosome. This binding site involves ribosomal protein L3 and is in the region of the ribosomal P site and peptidyl transferase center. By virtue of binding to this site, pleuromutilins inhibit peptidyl transfer, block P-site interactions, and prevent the normal formation of active 50S ribosomal subunits. Drug type: Approved. Small Molecule. Drug category: Antibacterial Agents ILX:0109984 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retention a preservation of the aftereffects of experience and learning that makes recall or recognition possible. Persistence of learned behavior or experience during a period when it is not being performed o r practiced. Retention is the second stage of memory after encoding and before retrival ILX:0109985 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Reteplase Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF). Pharmacology: Retavase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction. Mechanism of action: Retavase cleaves the Arg/Val bond in plasminogen to form plasmin. This in turn leads to the degradation of blood clots. Drug type: Approved. Biotech. Drug category: Thrombolytic Agents ILX:0109986 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Reticular formation A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 ). ILX:0109987 10 FDI Lab - SciCrunch.org 01/17/2023 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Reticular Mossy Fibers ILX:0109988 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Reticular nucleus of the thalamus of ABA 2009 ILX:0109989 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Reticulodromous A shape inhering in a bearer by virtue of having secondary branches branching into a reticulum toward the margin. ILX:0109990 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Reticulospinal tract The reticulospinal tract (or anterior reticulospinal tract) is an extrapyramidal motor tract which travels from the reticular formation. ILX:0109991 5 FDI Lab - SciCrunch.org 06/23/2020 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Reticulotegmental nucleus The tegmental pontine reticular nucleus (or pontine reticular nucleus of the tegmentum) is an area within the floor of the midbrain. This area is known to affect the cerebellum with its axonal projections. These efferent connections have been proven to project not only ipsilaterally, but also to decussate and project to the contralateral side of the vermis. It has also been shown that the projections from the tegmenti pontis to the cerebellar lobes are only crossed fibers. The n.r. tegmenti pontis also receives afferent axons from the cerebellum. This nucleus is known for its large amount of multipolar cells and its particularly reticular structure. The n.r. tegmenti pontis is topographically related to pontine nuclei (non-reticular), being just dorsal to them. The nucleus reticularis has been known to mediate eye movements, otherwise known as so-called saccadic movement. This makes sense concerning their connections as it would require a nucleus which receives and projects to the cerebellum to mediate that kind of complex circuitry. Also, behaviorally this makes sense as no one thinks about saccadic movements when scanning a room and the saccadic movements are not directly controlled by the cortex. The nuclei of the cerebellum are the most traditionally studied mostly because it is easy to see which nuclei degrade when the cerebellum is amputated. The neurons of the lateral reticular formation are very important for reflexes and the mediation of posture. It has been shown in cats that electrical stimulation of the reticular formation can make a standing cat lie down. Conversely if the cat is stimulated in an alternate spot it can make a lying cat stand. ILX:0109992 13 FDI Lab - SciCrunch.org 01/17/2023 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina The region of the eye consisting of ten-layered nervous tissue. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.* Definition Source: MeSH ILX:0109993 10 FDI Lab - SciCrunch.org 06/23/2020 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina amacrine cell Cell in the inner plexiform layer of the retina, consisting of multiple dendrites and no axon. It makes synaptic connections with bipolar cell terminals and ganglion cell dendrites, as well as other amacrine cell dendrites. Amacrine II cells have gap junctions with bipolar terminals and other amacrine cells, which are switched on for night time vision. ILX:0109994 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina B ganglion cell Sixty to eight neurons with small somata (12 to 24 micrometers in diameter), small dendritic fields (99 to 289 micrometers in diameter), and small axonal diameters (04. to 07. micrometers in diameter) make up Group RGB.We classified cells with a large soma and a large dendritic field as RGA, cells with a small to to medium to sized soma and a small to to medium to sized dendritic field as RGB, and cells with a small to to medium to sized soma but a medium to to to large dendritic field RGC. ILX:0109995 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina bipolar cell Small cell in the retina with one peripheral process connecting to terminals of photoreceptors and horizontal cells and the other process connecting to dendrites of ganglion cells and amacrine cells. It provides the straight-through pathway for visual responses from photoreceptors to ganglion cells. Several varieties are related to specific processing pathways. O ILX:0109996 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina bipolar cell off ILX:0109997 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina bipolar cell on ILX:0109998 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina bistratified amacrine cell Collator note: bistratified amacrine cells are not explicitly defined by Perry and Walker. Perry and Walker describe three types of bistratified amacrine cells, having thef dendrites or spines distributed in two strata as the common character. ILX:0109999 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina C ganglion cell Group RGC cells are defined as having small to to to medium cell bodies and medium to to to large dendritic fields. Their morphology was more heterogeneous than that of Groups RGA and RGB. We classified cells with a large soma and a large dendritic field as RGA, cells with a small to to medium to sized soma and a small to to medium to sized dendritic field as RGB, and cells with a small to to medium to sized soma but a medium to to to large dendritic field RGC. ILX:0110000 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina displaced amacrine cell ILX:0110001 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Retina ganglion cell The main principal neuron of the retina, whose axon projects to several sites in the brain: lateral geniculate nucleus on the pathway to visual cortex, superior colliculus and suprachiasmatic nucleus. It receives input from bipolar cells, and has synaptic inputs ILX:0110002 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex

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