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Total 959151 Results
| Label | Description | ILX | Version | Created CID | Modified Time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Neuron specific marker | A protein or other marker that is found exclusively or mainly in neurons and is used to differentiate neurons from other cell types in cell culture and tissue. | ILX:0107501 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit alpha-1 | The CHRNA1 gene encodes for this alpha 2 subunit that plays a role in acetlycholine binding/channel gating. (Adapted from Entrez Gene). | ILX:0107502 | 2 | FDI Lab - SciCrunch.org | 01/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit alpha-10 | A protein that is a translation product of the CHRNA10 gene or a 1:1 ortholog thereof. This nAchR subunit is required for the normal function of the olivocochlear system which is part of the auditory system. Furthermore selective block of α9α10 nicotinic acetylcholine receptors by the conotoxin RgIA has been shown to be analgesic in an animal model of nerve injury pain. (Adapted from PRotein Ontology and Wikipedia). | ILX:0107503 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit alpha-2 | A protein that is a translation product of the CHRNA2 gene or a 1:1 ortholog thereof. Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission.(Provided by RefSeq and PRotein Ontology). | ILX:0107504 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit alpha-4 | A protein that is a translation product of the CHRNA4 gene or a 1:1 ortholog thereof. | ILX:0107505 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit alpha-6 | A protein that is a translation product of the CHRNA6 gene or a 1:1 ortholog thereof. The ?6 subunit found in certain types of nicotinic acetylcholine receptors found primarily in the brain. Neural nicotinic acetylcholine receptors containing ?6 subunits are expressed on dopamine-releasing neurons in the midbrain, and dopamine release following activation of these neurons is thought to be involved in the addictive properties of nicotine. Due to their selective localisation on dopaminergic neurons, ?6-containing nACh receptors have also been suggested as a possible therapeutic target for the treatment of Parkinson's disease.(Adapted from PRotein Ontology and Wikipedia). | ILX:0107506 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | troy sincomb |
| Neuronal acetylcholine receptor subunit alpha-8 | This receptor it a protein that is a translation product of the CHRNA8 gene or a 1:1 ortholog thereof. NACHRA8 is a type of nicotinic acetylcholine receptor, consisting entirely of α8 subunits. This is the a type of neuronal-type II receptor subtype and these receptors are most present with in the brain. | ILX:0107507 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit alpha-9 | A protein that is a translation product of the CHRNA9 gene or a 1:1 ortholog thereof. This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells. (Adapted from PRotein Ontology and Entrez Gene). | ILX:0107508 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit beta-1 | This gene encodes the beta 1 subunit of the acetylcholine muscle receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. (Adapted from Entrez Gene). | ILX:0107509 | 2 | FDI Lab - SciCrunch.org | 01/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit beta-2 | A protein that is a translation product of the CHRNB2 gene or a 1:1 ortholog thereof. Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. (Adapted from PRotein Ontoloty and Entrez Gene). | ILX:0107510 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal acetylcholine receptor subunit beta-3 | A protein that is a translation product of the CHRNB3 gene or a 1:1 ortholog thereof. (Adapted from PRotein Ontology). | ILX:0107511 | 7 | FDI Lab - SciCrunch.org | 10/24/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | troy sincomb |
| Neuronal acetylcholine receptor subunit beta-4 | A protein that is a translation product of the CHRNB4 gene or a 1:1 ortholog thereof. The neuronal acetylcholine receptor is composed of an alpha and a beta subunit. Neuronal acetylcholine receptor beta-4 subunit can be combined with alpha- 2, alpha-3 or alpha-4 to give rise to functional receptor complexes. (Adapted from UniProtKB/Swiss-Prot) | ILX:0107512 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal birthday | The time that a neuronal progenitor cell leaves the cell cycle and gives rise to a postmitotic neuron. | ILX:0107513 | 5 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal Cell Body | The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. | ILX:0107514 | 6 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal Ceroid Lipofuscinosis | * A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluorescent wax-like lipid materials ( CEROID; LIPOFUSCIN) in neurons. There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive DEMENTIA; SEIZURES; and visual failure (MeSH). * Batten disease is a fatal, inherited disorder of the nervous system that begins in childhood. In some cases, the early signs are subtle, taking the form of personality and behavior changes, slow learning, clumsiness, or stumbling. Symptoms of Batten disease are linked to a buildup of substances called lipopigments in the body's tissues. Lipopigments are made up of fats and proteins. Because vision loss is often an early sign, Batten disease may be first suspected during an eye exam. Often, an eye specialist or other physician may refer the child to a neurologist. Diagnostic tests for Batten disease include blood or urine tests, skin or tissue sampling, an electroencephalogram (EEG), electrical studies of the eyes, and brain scans (NINDS Disease page). | ILX:0107515 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | troy sincomb |
| Neuronal intranuclear hyaline inclusion disease | Neuronal intranuclear hyaline inclusion disease is a rare neurodegenerative disease characterized pathologically by the presence of eosinophilic intranuclear inclusions in neuronal cells | ILX:0107516 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal nuclear antigen | A 46/48KD DNA-binding, neuron-specific protein found in nuclei which is present in most vertebrate CNS and PNS neuronal cell types. NeuN is widely used to label neurons, despite some shortcomings. A few neuronal cell types are not recognized by the NeuN antibody, such as cerebellar Purkinje cells and Golgi cells, olfactory Mitral cells and retinal photoreceptors. However the vast majority of neurons are strongly NeuN positive. NeuN immunoreactivity becomes obvious as neurons mature, typically after they have downregulated expression of Doublecortin, a marker seen in the earliest stages of neuronal development. (Adapted from Wikipedia: http://en.wikipedia.org/wiki/NeuN) | ILX:0107517 | 4 | FDI Lab - SciCrunch.org | 01/17/2023 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuronal tract tracing | An assay in which a tracer is injected into one or more regions of the nervous system or its targets that is taken up by cells, axons or axon terminals in order to determine axonal projections to or from that region. The tract tracing assay is used to ascertain the cells of origin that innervate a brain region, the synaptic target of these cells and the route via which the axons travel in the nervous system. | ILX:0107518 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuropathology | Subfield of pathology dealing with excised or postmortem examination of the nervous system tissues. | ILX:0107519 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Neuropathy | Medical term referring to disorders of the nerves of the peripheral nervous system (specifically excluding encephalopathy and myelopathy, which pertain to the central nervous system.)It is usually considered equivalent to peripheral neuropathy, which is defined as deranged function and structure of peripheral motor, sensory, and autonomic neurons, involving either the entire neuron or selected levels. According to some sources, a disorder of the cranial nerves can be considered a neuropathy. - adapted from Wikipedia | ILX:0107520 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
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