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Total 959151 Results
| Label | Description | ILX | Version | Created CID | Modified Time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mushroom body medial-vertical lobe arborizing neuron 2 | A neuron whose cell body is located in front of the ventral complex, ventral to the junction of the lobes in each brain hemisphere. The cell body fiber runs dorsomedially to the opposite hemisphere. The fiber from the opposite hemisphere runs laterally and bifurcates behind the tip of the beta' lobe. One of the fibers runs ventrally and enters the medial-most part of the beta lobe where it arborizes through the tip of the beta-p lobe to the lateral part of the beta lobe segment. The other fiber runs dorsolaterally towards the tip region of the vertical lobe and terminates in the superior neuropils. On the way, the fiber bifurcates and one of the branches terminates in the tip of the alpha' lobe. | ILX:0107241 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Mushroom body pedunculus-medial lobe and vertical lobe arborizing neuron 1 | A neuron, which is part of a cluster of at least seven neurons, whose cell body is located on the inferior neuropils, near the junction of the mushroom body lobes of each brain hemisphere. The cell body fiber bifurcates in front of the vertical lobes. One of these branches turns ventromedially to the tip of the medial lobe, whereas the other runs dorsally. The first branch innervates the medial lobe through the border between the gamma and beta' lobes and bifurcates both medially and laterally at the border between the beta and beta' lobes. One bundle of fibers runs medially to the opposite lobe, whereas the other runs laterally to the basal segments of the beta and alpha lobe as well as the core of the pedunculus. The second of the initial branches diverges in the superior neuropils near the tip of the vertical lobe. One branch turns laterally, runs through the anterior side of the vertical lobe and terminates in the superior intermediate protocerebrum and superior medial protocerebrum. Another branch turns medially and terminates in the anterior dorsal superior medial protocerebrum. Some branches turn laterally, innervating the posterior dorsal superior medial protocerebrum and posterior dorsal superior lateral protocerebrum, and terminate in the anterior dorsal superior lateral protocerebrum. | ILX:0107242 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Mushroom body pedunculus-medial lobe and vertical lobe arborizing neuron 2 | A neuron whose cell body is located on the inferior neuropils in each brain hemisphere. The cell body fiber runs posteriorly and bifurcates laterally and medially. The lateral branch arborizes in the lateral-most spur area of the gamma lobe and the inner core of the pedunculus. The medial branch bifurcates in front of the middle segment of the medial lobe. One of the branches projects to the contralateral medial lobe. On the way to the opposite hemisphere, in the medial segment of the medial lobe, one fiber branches out, turns dorsolaterally and arborizes in the inferior neuropils. Some fibers extend further to the superior neuropils. The other branch turns dorsally, runs along the alpha lobe and terminates in the posterior tip of the alpha' lobe. | ILX:0107243 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Mushroom body pedunculus-medial lobe arborizing neuron 1 | A neuron whose cell body is located on the inferior neuropils, lateral to the calyx of each brain hemisphere. The cell body fiber runs anteriormedially and diverges above the ellipsoid body, with most of the branches arborizing in the anterior part of the inferior neuropils. One fiber turns dorsolaterally, runs in front of the anterior surface of the vertical lobe and terminates in the middle of the inferior neuropils. On the way, one fiber branches off and arborizes in the anterior and middle of the superior neuropils. Another fiber turns ventromedially and projects to the opposite hemisphere. A third fiber turns ventrolaterally, runs in front of the anterior surface of the gamma lobe and then below the gamma lobe, and arborizes in the spur of the gamma lobe and inner core of the pedunculus. | ILX:0107244 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Mushroom body pedunculus-vertical lobe arborizing neuron 1 | A neuron, which is part of a cluster of at least two neurons, whose cell body is located on the inferior neuropils, near the junction of the mushroom body lobes of each brain hemisphere. The cell body fiber bifurcates near the vertical lobe. One of these fibers turns ventromedially to the tip of the medial lobe, whereas the other runs dorsally. The ventromedially directed branch innervates the medial lobe through the border between the gamma and beta' lobes. One branch runs medially to the opposite medial lobe whereas the other runs laterally to the basal segments of the alpha lobe and the inner core of the pedunculus. From the alpha lobe, one branch runs dorsally, turns dorsolaterally behind the alpha lobe and terminates in the posterior of the superior neuropils where it arborizes and further spreads laterally to the anterior dorsal superior lateral protocerebrum and the inferior neuropils. | ILX:0107245 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Mushroom body ventral lobe arborizing neuron 1 | A single neuron whose cell body is located on the superior neuropils lateral to the calyx of each brain hemisphere. The cell body fiber projects anterior-medially and forms branches in the superior neuropils posterior to the vertical lobes. One of these branches projects to the opposite hemisphere and others project to the vertical lobe and form extensive arborizations in the middle segment of both the alpha and alpha' lobes. | ILX:0107246 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Mushroom body ventral lobe arborizing neuron 3 | A neuron, which is one of approximately two neurons per brain hemisphere, whose cell body is located in the dorsal-most area of the subesophageal ganglion, ventromedial to the antennal lobe. The cell body fiber ascends through the median bundle to the level of the gamma lobe, and then projects towards the tip of the alpha lobe where it forms extensive arborization. On the way to the alpha lobe, several fibers branch off with some arborizing in the superior neuropils, and others arborize in this region before turning anteriorly and terminating in the anterior dorsal superior medial protocerebrum. | ILX:0107247 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Mushroom body ventral lobe arborizing neuron 4 | One of approximately two neurons per brain hemisphere whose cell body is located in the dorsal-most area of the subesophageal ganglion, ventromedial to the antennal lobe. The cell body fiber ascends through the median bundle to the level of the gamma lobe before making a steep lateral turn and forming extensive branches in the inferior neuropils. Some branches further arborize in the superior neuropils posterior to the vertical lobe. The main fiber further projects towards the vertical lobe and arborizes extensively in the alpha' lobe. | ILX:0107248 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Mushroom dendritic spine | Large dendritic spines characterized by an enlarged head relative to neck diameter, often containing a spine apparatus and perforated post-synaptic density | ILX:0107249 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Mushroom Spine Quality | Characterized by the diameter of the head being much greater than that of the neck (Harris et. al 1992). | ILX:0107250 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Music comprehension-production | Subjects listen to music passively or are asked to sing overtly. | ILX:0107251 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Mustela putorius furo | ILX:0107252 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Mustelidae | ILX:0107253 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex | |
| Mustelinae | ILX:0107254 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex | |
| Mutant Drosophila | Transgenically modified drosophila. | ILX:0107255 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Mutant mouse strain | ILX:0107256 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex | |
| Mutated | ILX:0107257 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex | |
| Myasthenia Gravis | A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition (MeSH). | ILX:0107258 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
| Myasthenia Gravis, Ocular | ILX:0107259 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex | |
| Mycophenolate mofetil | Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA), an immunosuppressive agent, inosine monophosphate dehydrogenase (IMPDH) inhibitor. Pharmacology: Mycophenolate mofetil is a prodrug of mycophenolic acid, an antibiotic substance derived from Penicillium stoloniferum. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. Mechanism of action: Mycophenolate mofetil is hydrolyzed to form mycophenolic acid (MPA), which is the active metabolite. MPA is a potent, selective, uncompetitive, and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), and therefore inhibits the de novo pathway of guanosine nucleotide synthesis without incorporation into DNA. Because T- and B-lymphocytes are critically dependent for their proliferation on de novo synthesis of purines, whereas other cell types can utilize salvage pathways, MPA has potent cytostatic effects on lymphocytes. MPA inhibits proliferative responses of T- and B-lymphocytes to both mitogenic and allospecific stimulation. Addition of guanosine or deoxyguanosine reverses the cytostatic effects of MPA on lymphocytes. MPA also suppresses antibody formation by B-lymphocytes. MPA prevents the glycosylation of lymphocyte and monocyte glycoproteins that are involved in intercellular adhesion to endothelial cells and may inhibit recruitment of leukocytes into sites of inflammation and graft rejection. Mycophenolate mofetil did not inhibit early events in the activation of human peripheral blood mononuclear cells, such as the production of interleukin-1 (IL-1) and interleukin-2 (IL-2), but did block the coupling of these events to DNA synthesis and proliferation. Drug type: Approved. Investigational. Small Molecule. Drug category: Anti-Inflammatory Agents, Non-Steroidal. Antineoplastic Agents. Dermatologic Agents. Enzyme Inhibitors. Immunosuppressive Agents | ILX:0107260 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/09/2016 | 0 | NeuroLex | NeuroLex |
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