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Total 959151 Results

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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Miscibility A quality of a liquid to mix with (dissolve in) another liquid. ILX:0107001 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Misfolded Molecular Quality Pertains to formation of protein aggregates. There are varying degrees of "misfolded". ILX:0107002 5 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex troy sincomb
Mislocalised Placement which is in an abnormal location. ILX:0107003 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mislocalised anteriorly Mislocalised which is towards the front of an organism. ILX:0107004 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mislocalised dorsally Mislocalised which is towards the back or upper surface of an organism. ILX:0107005 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mislocalised laterally Mislocalised which is towards the side of an organism. ILX:0107006 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mislocalised medially Mislocalised which is towards the middle of an organism. ILX:0107007 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mislocalised posteriorly Mislocalised which is towards the rear of an organism. ILX:0107008 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mislocalised ventrally Mislocalised which is towards the abdomen of an organism. ILX:0107009 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mismatch negativity paradigm behavioral paradigm that assesses a response to non-attended stimuli which are dissimilar to the majority of stimuli presented. ILX:0107010 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Misoprostol A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties. (PubChem) Pharmacology: Misoprostol is a prostaglandin E1 (PGE1) analogue used for the treatment and prevention of stomach ulcers. When administered, misoprostol stimulates increased secretion of the protective mucus that lines the gastrointestinal tract and increases mucosal blood flow, thereby increasing mucosal integrity. It is sometimes co-prescribed with non-steroidal anti-inflammatory drugs (NSAIDs) to prevent the occurrence of gastric ulceration, a common adverse effect of the NSAIDs. Mechanism of action: Misoprostol seems to inhibit gastric acid secretion by a direct action on the parietal cells through binding to the prostaglandin receptor. The activity of this receptor is mediated by G proteins which normally activate adenylate cyclase. The indirect inhibition of adenylate cyclase by Misoprostol may be dependent on guanosine-5-triphosphate (GTP). The significant cytoprotective actions of misoprostol are related to several mechanisms. These include: 1. Increased secretion of bicarbonate, 2. Considerable decrease in the volume and pepsin content of the gastric secretions, 3. It prevents harmful agents from disrupting the tight junctions between the epithelial cells which stops the subsequent back diffusion of H+ ions into the gastric mucosa, 4. Increased thickness of mucus layer, 5. Enhanced mucosal blood flow as a result of direct vasodilatation, 6. Stabilization of tissue lysozymes/vascular endothelium, and 7. Improvement of mucosal regeneration capacity. Drug type: Approved. Small Molecule. Drug category: Abortifacient Agents. Abortifacient Agents, Nonsteroidal. Anti-Ulcer Agents. Oxytocics. Prostaglandins ILX:0107011 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Misrouted A mistakenly taken course, way, or passage; ill-routed. ILX:0107012 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
MIT License A free software license created by Massachusetts Institute of Technology (MIT). It is a permissive license, meaning it permits reuse within proprietary software on the condition that the MIT license is distributed with the new software.NITRC definition: The MIT license, also the X Consortium License, or a derivative, is fairly permissive, placing few restrictions on the developer or user. As a developer, you may distribute source or binaries (with or without source code). As a tool user, you may modify and redistribute this tool or resource. If source code is distributed, a user may browse the source code to understand the tool's workings, modify the tool to better suit local needs, and may share a modified version. If source code is not distributed, a user may still redistribute the tool as part of another package. ILX:0107013 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex troy sincomb
Mitiglinide Mitiglinide is a drug for the treatment of type 2 diabetes .Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) (K(ATP)) channels in pancreatic beta-cells. Pharmacology: Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs. It is approved for use in Japan but has not yet gained FDA approval. Mechanism of action: Mitiglinide is a novel antidiabetic agent for the treatment of type-2 diabetes mellitus. Its chemical structure is similar to that of sulphonylureas. Mitiglinide exerts a hypoglycaemic effect with rapid onset and short duration of action, by transiently increasing insulin secretion. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) (K(ATP)) channels (Kir6.2/SUR1 complex, KATP channels) in pancreatic beta-cells. Mitiglinide may also activate ryanodine receptors. Drug type: Approved. Investigational. Small Molecule. Drug category: Hypoglycemic Agents ILX:0107014 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mitochondrial Adhaerens Complex An adherens plaque attached by filamentous strands to mitochondrion found in large synaptic terminals in the calyx of Held. The peripheral membrane facing the plaque is flattened and faces the synaptic presynaptic membrane (Perkins and Ellisman, 2005). ILX:0107015 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mitochondrial Chromosome A chromosome found in the mitochondrion of a eukaryotic cell (Gene Ontology). ILX:0107016 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mitochondrial DNA Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial genome is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins (MSH). ILX:0107017 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mitochondrial Intermembrane Space The region between the inner and outer lipid bilayers of the mitochondrial envelope. (Gene Ontology). ILX:0107018 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mitochondrial Lumen Interior portion of mitochondrion bounded by the inner mitochondrial membrane and cristae membranes and containing the mitochondrial matrix. Does not include the crista or crista lumen. ILX:0107019 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Mitochondrial Matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes concerned with fatty-acid oxidation and enzymes of the tricarboxylic acid cycle (Gene Ontology). ILX:0107020 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex

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