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Total 959151 Results

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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
L2 GRN Gustatory receptor neuron responsive to high concentrations of salt (Montell, 2009) and bitter compounds (Meunier et al., 2003). ILX:0105959 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Label Style Selection A code sequence that indicates the label style selection. ILX:0105960 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Label Text The text used in the image label. ILX:0105961 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Labeled line code A method of coding information based on specific neuronal pathways, or private lines that distinguish activity in one pathway from that in another pathway. ILX:0105962 5 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Labetalol Blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive. (PubChem) Pharmacology: Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output. Mechanism of action: Labetalol has two asymmetric centers and therefore, exists as a molecular complex of two diastereoisomeric pairs. Dilevalol, the R,R' stereoisomer, makes up 25% of racemic labetalol. Labetalol HCl combines both selective, competitive, alpha-1-adrenergic blocking and nonselective, competitive, beta-adrenergic blocking activity in a single substance. In man, the ratios of alpha- to beta- blockade have been estimated to be approximately 1:3 and 1:7 following oral and intravenous (IV) administration, respectively. Beta-2-agonist activity has been demonstrated in animals with minimal beta-1-agonist (ISA) activity detected. In animals, at doses greater than those required for alpha- or beta- adrenergic blockade, a membrane stabilizing effect has been demonstrated. Drug type: Approved. Small Molecule. Drug category: Adrenergic alpha-Antagonists. Adrenergic beta-Antagonists. Antihypertensive Agents. Sympatholytics ILX:0105963 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex troy sincomb
Labral sense organ neuron ILX:0105964 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lack of fertily in offspring A fertility quality inhering in a bearer by virtue of making its offspring sterile. ILX:0105965 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lacking function ILX:0105966 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lacking processual parts A relational quality of occurent inhering in a bearer by virtue of its lacking a processual part as specified by the additional entity. ILX:0105967 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lacks all parts of type A relational quality in which the bearer entity has no parts of the specified type. The bearer of this quality has part ILX:0105968 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lacks parts or has fewer parts of type The bearer of this quality has part ILX:0105969 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lactation The secretion of milk by the mammary gland ILX:0105970 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lactulose A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887) Pharmacology: Therapeutically, lactulose has laxative and ammonia-detoxifying actions. In treating constipation lactulose metabolites draw water into the bowel, causing a cathartic effect through osmotic action. Mechanism of action: Lactulose is a synthetic sugar used in the treatment of constipation and liver disease. It consists of the monosaccharides fructose and galactose. In the colon, lactulose is broken down primarily to lactic acid, and also to small amounts of formic and acetic acids, by the action of via evolved-beta galactosidase from colonic bacteria, which results in an increase in osmotic pressure and slight acidification of the colonic contents. This in turn causes an increase in stool water content and softens the stool. In treating heptic diseases (hepatic encephalopathy) it is thought that lactulose draws out ammonia from the body in the same way that it draws out water into the colon. Drug type: Approved. Small Molecule. Drug category: Gastrointestinal Agents ILX:0105971 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lafora Progressive Myoclonic Epilepsy A form of stimulus sensitive myoclonic epilepsy inherited as an autosomal recessive condition. The most common presenting feature is a single seizure in the second decade of life. This is followed by progressive myoclonus, myoclonic seizures, tonic-clonic seizures, focal occipital seizures, intellectual decline, and severe motor and coordination impairments. Most affected individuals do not live past the age of 25 years. Concentric amyloid (Lafora) bodies are found in neurons, liver, skin, bone, and muscle (MeSH). ILX:0105972 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lagomorpha ILX:0105973 5 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lambert-Eaton Myasthenic Syndrome An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve (MeSH). ILX:0105974 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lamellar Body Membranous inclusions composed of stacks of unperforated cisternae derived from the granular endoplasmic reticulum. Cisternae are spaced at intervals of about 30-40 nm (Peters, Palay and Webster, 1991). ILX:0105975 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lamellar Cristae Quality Refers to cristae with a flattened, extended appearance. ILX:0105976 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lamina dissecans of entorhinal cortex Acellular layer of entorhinal cortex, usually identified as layer IV in some nomenclatures (Paxinos, The rat nervous system, Academic Press, 1995, pg 473-474). ILX:0105977 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Lamina of septum pellucidum One of two layers of both white and gray matter of the septum pellucidum. During fetal development there is a space between the two laminae called the cavum septum pellucidum which, in ninety per cent of cases, disappears during infancy. ILX:0105979 10 FDI Lab - SciCrunch.org 01/17/2023 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex

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