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Total 959151 Results
| Label | Description | ILX | Version | Created CID | Modified Time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Item recognition activity | ILX:0105759 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Item recognition paradigm | A behavioral paradigm where sets of target items are presented at the outset and the recognition of one or more of those items vs unfamiliar items is tested using a probe item. | ILX:0105760 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Item recognition task | No definition submitted yet. | ILX:0105761 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Itraconazole | One of the triazole antifungal agents that inhibits cytochrome P-450-dependent enzymes resulting in impairment of ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis & aspergillosis. (PubChem) Pharmacology: Itraconazole is an imidazole/triazole type antifungal agent. Itraconazole is a highly selective inhibitor of fungal cytochrome P-450 sterol C-14 -demethylation via the inhibition of the enzyme cytochrome P450 14-demethylase. This enzyme converts lanosterol to ergosterol, and is required in fungal cell wall synthesis. The subsequent loss of normal sterols correlates with the accumulation of 14 -methyl sterols in fungi and may be partly responsible for the fungistatic activity of fluconazole. Mammalian cell demethylation is much less sensitive to fluconazole inhibition. Itraconazole exhibits in vitro activity against Cryptococcus neoformans and Candida spp. Fungistatic activity has also been demonstrated in normal and immunocompromised animal models for systemic and intracranial fungal infections due to Cryptococcus neoformans and for systemic infections due to Candida albicans. Mechanism of action: Itraconazole interacts with 14- demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Itraconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis. Drug type: Approved. Investigational. Small Molecule. Drug category: Antifungal Agents. Antifungals. Antiprotozoal Agents. Antiprotozoals | ILX:0105762 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Ivermectin | Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum anti-parasite medication, traditionally used against worms (except tapeworms), but more recently found to be effective against most mites and some lice too. It is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and enterobiasis). Pharmacology: Ivermectin is a semisynthetic, anthelminitic agent. It is an avermectin which a group of pentacyclic sixteen-membered lactone (i.e. a macrocyclic lactone disaccharide) derived from the soil bacterium Streptomyces avermitilis. Avermectins are potent anti-parasitic agents. Ivermectin is the most common avermectin. It is a broad spectrum antiparasitic drug for oral administration. It is sometimes used to treat human onchocerciasis (river blindness). It is the mixture of 22,23-dihydro-avermectin B1a (at least 90%) and 22,23-dihydro-avermectin B1b (less than 10%). Mechanism of action: Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite. Ivermectin also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission. Ivermectin may also impair normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms. Drug type: Approved. Small Molecule. Drug category: Anthelmintics. Antinematodal Agents. Antiprotozoal Agents | ILX:0105763 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| IVUS Acquisition | This attribute denotes which of the following defined terms describes the method used to acquire the IVUS Images. Required if Modality (0008,0060) | ILX:0105764 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| IVUS Gated Rate | Required if IVUS Acquisition (0018,3100) value is GATED_PULLBACK. Specified in units of mm/beat. | ILX:0105765 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| IVUS Pullback Rate | Required if IVUS Acquisition (0018,3100) value is MOTOR_PULLBACK. Specified in units of mm/sec. | ILX:0105766 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| IVUS Pullback Start Frame Number | The IVUS Pullback Start Frame Number (0018,3103) specifies the frame number of a IVUS multiframe. Required if IVUS Acquisition (0018,3100) value is MOTOR_PULLBACK or GATED_PULLBACK. | ILX:0105767 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| IVUS Pullback Stop Frame Number | Frame number at which the motorized portion of the acquisition is complete. | ILX:0105768 | 6 | FDI Lab - SciCrunch.org | 08/28/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| IWT | Government agency for Innovation by Science and Technology that helps Flemish companies and research centers in realizing their research and development projects by offering them financial funding, advice and a network of potential partners in Flanders and abroad. They also support the Flemish Government in its innovation policy. | ILX:0105769 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Janssen | Pharmaceutical company that brings products, services and solutions to people throughout the world to address and solve some unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Their research and development strategy focuses on identifying medical needs and harnessing the best science in the world, whether from their own laboratories or through strategic relationships and collaborations. | ILX:0105770 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Janssen Pharmaceuticals Inc. | A pharmaceutical company of Johnson & Johnson that provides medicines for an array of health concerns in several therapeutic areas, including: attention deficit hyperactivity disorder (ADHD), general medicine (acid reflux disease, infectious diseases), mental health (bipolar I disorder, schizophrenia), neurologics (Alzheimer's disease, epilepsy, migraine prevention and treatment), pain management, and women's health. They have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners, from clinics to hospitals. | ILX:0105771 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Japan Society for the Promotion of Science | ILX:0105772 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Japanese macaque | The species *Macaca fuscata* (Japanese macaque) belongs to the family of *cercopithecidae* (old world monkeys). | ILX:0105773 | 6 | FDI Lab - SciCrunch.org | 01/17/2023 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Japanese quail | ILX:0105774 | 5 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| JISC | Joint Information Systems Committee (JISC) is the UK's expert on information and digital technologies for education and research. JISC inspires UK colleges and universities in the innovative use of digital technologies, helping to maintain the UK's position as a global leader in education. JISC helps institutions make best use of technology to manage all aspects of their business. JISC provides access to the world-class Janet (UK) network, quality digital resources and a range of specialist advisory services.JISC provides:* A world-class network - JANET* Access to electronic resources* New environments for learning, teaching and research* Guidance on institutional change* Advisory and consultancy services* Regional support - JISC RSCsPartnershipsJISC develops partnerships to enable the UK education and research communities to engage in national and global collaborations to overcome the challenges of delivering world-class ICT solutions and services. Funding OpportunitiesJISC funds a wide range of infrastructure, services, innovative projects and studies. A large number of these originate from a successful response to a grant funding call (previously known as a JISC Circular), inviting eligible HE and FE institutions to bid for project funding. JISC also procures other activities (usually studies such as an evaluation or market research), through invitations to tender which are available to other organizations to bid against. JISC is the name of our organization. Historically, it stood for Joint Information Systems Committee. | ILX:0105775 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Job resource | A resource that provides listings of employment opportunities. | ILX:0105776 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Johnston organ neuron | Scolopidial (mechanosensory) neuron of Johnston's organ. Its axon innervates the antennal mechanosensory and motor center. | ILX:0105777 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Johnston organ neuron activated by tonic anterior arista deflection | Johnston's organ neuron tonically activated by anterior arista deflection and required for wind-induced suppression of locomotion behaviour (WISL, Yorozu et al., 2009). These neurons project to zone C of the antennal mechanosensory and motor center. | ILX:0105778 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
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