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Ifosfamide
|
Positional isomer of cyclophosphamide which is active as an alkylating agent and an immunosuppressive agent. (PubChem) Pharmacology: Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed. Mechanism of action: After metabolic activation, active metabolites of ifosfamide alkylate or bind with many intracellular molecular structures, including nucleic acids. The cytotoxic action is primarily due to cross-linking of strands of DNA and RNA, as well as inhibition of protein synthesis. Drug type: Approved. Small Molecule. Drug category: Antineoplastic Agents. Antineoplastic Agents, Alkylating. Immunosuppressive Agents
|
ILX:0105219
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
III1 motor neuron
|
|
ILX:0105220
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
III3 motor neuron
|
|
ILX:0105221
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Illumination
|
Luminance of a hypothetical viewing device illuminating a piece of monochrome transmissive film, or for the case of reflective media, luminance obtainable from diffuse reflection of the illumination present. Expressed as L0, in candelas per square meter (cd/m2). May be used together with Reflected Ambient Light (2010,0160) to recover Optical Density information from P-Values.
|
ILX:0105222
|
5
|
FDI Lab - SciCrunch.org
|
08/28/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
troy sincomb |
|
Illumination Type Code Sequence
|
Coded value for illumination. Zero or one item shall be present in the sequence.
|
ILX:0105223
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Iloprost
|
Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH). Pharmacology: Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost dilates systemic and pulmonary arterial vascular beds. It also affects platelet aggregation but the relevance of this effect to the treatment of pulmonary hypertension is unknown. The two diastereoisomers of iloprost differ in their potency in dilating blood vessels, with the 4S isomer substantially more potent than the 4R isomer. Mechanism of action: Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, such as carbaprostacyclin. Iloprost binds with equal affinity to human prostacyclin (Prostanoid IP) and prostaglandin EP1 receptors. Iloprost constricts the ilium and fundus circular smooth muscle as strongly as prostaglandin E2 (PGE2) itself. Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. All of these properties help to antagonize the pathological changes that take place in the small pulmonary arteries of patients with pulmonary hypertension. Drug type: Approved. Investigational. Small Molecule. Drug category: Antihypertensive Agents
|
ILX:0105224
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image
|
An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface.
|
ILX:0105225
|
7
|
FDI Lab - SciCrunch.org
|
07/28/2022
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
Jeffrey Grethe |
|
Image acquisition protocol
|
Protocol that specifies the acquisition of imaging data
|
ILX:0105226
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image acquisition software
|
|
ILX:0105227
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image analysis software
|
|
ILX:0105228
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image Area Dose Product
|
Total area-dose-product to which the patient was exposed, accumulated over the complete Performed Procedure Step and measured in dGy*cm*cm, including fluoroscopy.
|
ILX:0105229
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image Center Point Coordinates Sequence
|
The coordinates of the center point of the Image in the Slide Coordinate System Frame of Reference. This sequence shall contain exactly one item.
|
ILX:0105230
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image collection
|
A collection of images, without a database query function.
|
ILX:0105231
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image Comments
|
User-defined comments about the image.
|
ILX:0105232
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image creation
|
A planned process that captures an image of an object.
|
ILX:0105233
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image Frame Origin
|
Frame number of Multi-frame Image to which this overlay applies; frames are numbered from 1.
|
ILX:0105234
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image Horizontal Flip
|
Whether or not to flip the image horizontally after any Image Rotation has been applied such that the left side of the image becomes the right side.
|
ILX:0105235
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image ID
|
User or equipment generated Image identifier.
|
ILX:0105236
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image Index
|
An index identifying the position of this image within a PET Series.
|
ILX:0105237
|
4
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Image interpretation attribute
|
Attributes about the radiological interpretation of the image
|
ILX:0105238
|
3
|
FDI Lab - SciCrunch.org
|
06/18/2018
|
FDI Lab - SciCrunch.org |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |