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Total 959151 Results

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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Dendrite A branching protoplasmic process of a neuron that receive and integrate signals coming from axons of other neurons, and convey the resulting signal to the body of the cell (Gene Ontology)., One of several similar processes that issue from the perikaryon of a neuron, generally specialized for receiving synaptic input from other neurons or transduction of signals from the environment. ILX:0103021 7 FDI Lab - SciCrunch.org 01/17/2023 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendrite Quality Characterization based on high or low density of classical spines on dendrites. ILX:0103022 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic A shape inhering in a bearer by virtue of having smaller branches arising from larger branches. Resembling a tree in branching structure. ILX:0103023 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic action potential Action potentials generated in the dendrites of a neuron. ILX:0103024 5 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic arborizing neuron Sensory multidendritic neuron of the PNS with branching dendrites that spread directly below and in close association with the epidermal cell layer. ILX:0103025 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic Branch Refers to dendrites arising from another dendrite. ILX:0103026 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic Growth Cone ILX:0103027 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic Microtubule ILX:0103028 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic Shaft Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines (Gene Ontology). ILX:0103029 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic spine Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity (Gene Ontology). ILX:0103030 7 FDI Lab - SciCrunch.org 01/17/2023 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendritic Tree The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. ILX:0103031 9 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendroaxonic synapse The synapse made by an axon terminal of one neuron onto the axon of another. ILX:0103032 5 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendronotidae ILX:0103033 6 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendronotina ILX:0103034 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendronotoidea ILX:0103035 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus ILX:0103036 6 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus dalli ILX:0103037 6 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus frondosus ILX:0103038 6 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Dendronotus iris ILX:0103039 6 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Denileukin diftitox A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system. Pharmacology: Denileukin diftitox (Ontak) directs the cytocidal action of diphtheria toxin to cells which express the IL-2 receptor. The human IL-2 receptor exists in three forms, low (CD25), intermediate (CD122/CD132) and high (CD25/CD122/CD132) affinity. Malignant cells expressing one or more of the subunits of the IL-2 receptor are found in certain leukemias and lymphomas including cutaneous T-cell lymphoma (CTCL). Ontak interacts with the high affinity IL-2 receptor on the cell surface and inhibits cellular protein synthesis, resulting in cell death within hours. Mechanism of action: Denileukin diftitox binds to the high-affinity IL-2 receptor complex. The IL-2 receptor (Tac) subunit is expressed on activated but not resting lymphocytes. The diphtheria toxin associated with Ontak then selectively kills the IL-2 bearing cells. Drug type: Approved. Biotech. Investigational. Drug category: Antineoplastic Agents ILX:0103040 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex

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