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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Physicians of Record Names of the physician(s) who are responsible for overall patient care at time of Study (see for Performing Physician) ILX:0108863 5 FDI Lab - SciCrunch.org 08/28/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Physicians of Record Identification Sequence Identification of the physician(s) who are responsible for overall patient care at time of Study. ILX:0108864 5 FDI Lab - SciCrunch.org 08/28/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Physicians Reading Study Identification Sequence Identification of the physician(s) reading the Study. ILX:0108865 6 FDI Lab - SciCrunch.org 08/28/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Physiological model A mathematical description of the complex physical and temporal dependencies between a set of related biological entities and their immediated environment. ILX:0108866 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Physiological role ILX:0108867 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Physiological state A monadic quality of occurrent inhering in a bearer by virtue of the state of its mechanical, physical, and biochemical processes. ILX:0108868 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Physiology The functions of living organisms and their constituent parts. ILX:0108869 5 FDI Lab - SciCrunch.org 08/01/2022 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Physiology Instrument A device or instrument that is used to measure attributes of living cells, tissues or organisms while the cells, tissues or organism is alive. ILX:0108870 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Physostigmine A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity. (PubChem) Pharmacology: Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia. Mechanism of action: By interfering with the metabolism of acetylcholine, physostigmine indirectly stimulates both nicotinic and muscarinic receptors. Drug type: Approved. Small Molecule. Drug category: Cholinesterase Inhibitors. Miotics ILX:0108871 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Phytonadione Phytonadione is often called vitamin K1. It is a fat-soluble vitamin that is stable to air and moisture but decomposes in sunlight. It is found naturally in a wide variety of green plants. Phylloquinone is also an antidote for coumatetralyl. Vitamin K is needed for the posttranslational modification of certain proteins, mostly required for blood coagulation. Pharmacology: Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X). Mechanism of action: Vitamin K is an essential cofactor for the gamma-carboxylase enzymes which catalyze the posttranslational gamma-carboxylation of glutamic acid residues in inactive hepatic precursors of coagulation factors II, VII, IX and X. Gamma-carboxylation converts these inactive precursors into active coagulation factors which are secreted by hepatocytes into the blood. Supplementing with Phytonadione results in a relief of vitamin K deficiency symptoms which include easy bruisability, epistaxis, gastrointestinal bleeding, menorrhagia and hematuria. Drug type: Approved. Small Molecule. Drug category: Antifibrinolytic Agents. Vitamins. Vitamins (Vitamin K) ILX:0108872 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pial Cell ILX:0108873 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pial membrane The innermost layer of the leptomeninges, consisting of a delicate membrane closely covering the surface of the brain and spinal cord,and lying under the arachnoid membrane. The pia, unlike the arachnoid, extends into the sulci in gyrencephalic animals. ILX:0108874 10 FDI Lab - SciCrunch.org 06/23/2020 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pick Body Pick Bodies are composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component. Pick bodies also stain for ubiquitin, alpha-synuclein, and apolipoprotein E. ILX:0108875 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pick's Disease A non-Alzheimers dementia characterized by focal atrophy of the frontal and anterior temporal regions of the brain. It usually occurs in an age range of 35-75 and it is more common in individuals with a positive family history of dementia. ILX:0108876 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Picrotoxin A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. (PubChem) Pharmacology: Picrotoxin is a toxin obtained from the seeds of the shrub Anamirta cocculus. It is used as a central nervous system stimulant, antidote, convulsant, and GABA (gamma aminobutyric acid) antagonist. It is a noncompetitive antagonist at GABAA receptors and thus a convulsant. Picrotoxin blocks the GABAActivated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially barbiturates. Mechanism of action: Picrotoxin antagonizes the GABAA receptor channel directly, which is a ligand-gated ion channel concerned chiefly with the passing of chloride ions across the cell membrane. Therefore picrotoxin prevents Cl- channel permeability and thus promtes an inhibitory influence on the target neuron. Picrotoxin reduces conductance through the channel by reducing not only the opening frequency but also the mean open time. Picrotoxin also antagonizes GABAC receptors (also called GABAA-rho receptors) but the result of this action is not known. The GABAC receptor is also linked to chloride channels, with distinct physiological and pharmacological properties. In contrast to the fast and transient responses elicited from GABAA receptors, GABAC receptors mediate slow and sustained responses. Drug type: Approved. Small Molecule. Drug category: Anti-barbituates. Antidotes. Central Nervous System Stimulants. Convulsants. GABA Antagonists. GABA receptor antagonists. Stimulants ILX:0108877 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Picture naming task participants are shown pictures of objects and asked to identify the item. ILX:0108878 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Picture set test No definition submitted yet. ILX:0108879 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Picture-word stroop task No definition submitted yet. ILX:0108880 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pigment ILX:0108881 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pigment Epithelial Cell Located in the sub-retinal space, these cells form the sub-retinal blood-brain barrier and contain light-absorbing melanin pigment granules ILX:0108882 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex

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