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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Heterotrimeric G proteins ILX:0104979 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexachlorobutadiene Organic Compound;Solvent;Organochloride; Hexachlorobutadiene is a man-made chemical primarily produced as a by-product in the production of carbon tetrachloride and tetrachloroethene. It is also used to make rubber compounds, lubricants, in gyroscopes, as a heat transfer liquid, as a hydraulic fluid, and as a solvent. ILX:0104980 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexachlorocyclohexane, beta- Organic Compound;Pesticide;Organochloride; Hexachlorocyclohexane, Beta- is one of eight isoforms of the commercially manufactured chemical hexachlorocyclohexane. It is used as an insecticide on fruit, vegetables, and forest crops and is also available as a prescription (lotion, cream, or shampoo) to treat head and body lice, and scabies. ILX:0104981 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexachlorocyclohexane, delta- Organic Compound;Pesticide;Organochloride; Hexachlorocyclohexane, Delta- is one of eight isoforms of the commercially manufactured chemical hexachlorocyclohexane. It is used as an insecticide on fruit, vegetables, and forest crops and is also available as a prescription (lotion, cream, or shampoo) to treat head and body lice, and scabies. ILX:0104982 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexachlorocyclohexane, gamma- Organic Compound;Pesticide;Organochloride; Hexachlorocyclohexane, Gamma- is one of eight isoforms of the commercially manufactured chemical hexachlorocyclohexane. It is used as an insecticide on fruit, vegetables, and forest crops and is also available as a prescription (lotion, cream, or shampoo) to treat head and body lice, and scabies. ILX:0104983 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexachlorophene A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797) Pharmacology: Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue. Mechanism of action: The primary mechanism of action of hexachlorophene, based on studies with Bacillus megatherium, is to inhibit the membrane-bound part of the electron transport chain, respiratory D-lactate dehydrogenase. It induces leakage, causes protoplast lysis, and inhibits respiration. Drug type: Approved. Small Molecule. Drug category: Anti-Infective Agents, Local. Anti-Infectives ILX:0104984 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexafluronium bromide Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. It is known to bind and block the activity of plasma cholinesterases. Pharmacology: Hexafluronium bromide is a cholinesterase antagonist that can be used to prolong the relaxation effects of succinylcholine or suxamethonium chloride. Suxamethonium acts as a depolarizing muscle relaxant. It imitates the action of acetylcholine at the neuromuscular junction and is degraded by pseudocholinesterase, a plasma cholinesterase. The prolonged stimulation of the acetylcholine receptor results first in disorganized muscle contractions, then in profound relaxation. Cholinesterases catalyze the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. There are two types of cholinesterase acetylcholinesterase and pseuodocholinesterase. The first hydrolyses acetylcholine more quickly; the latter hydrolyses butyrylcholine and succinylcholine more quickly. An absence or mutation of the pseudocholinesterase enzyme leads to a medical condition known simply as pseudocholinesterase deficiency. This is a silent condition that only manifests itself when people who have the deficiency receive the muscle relaxants succinylcholine or mivacurium during a surgery. Mechanism of action: Hexafluronium bromide is a non-competitive reversible inhibitor of human plasma cholinesterase or pseudocholinesterase. Drug type: Approved. Small Molecule. Drug category: Muscle Relaxants ILX:0104985 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexaploid A polyploidy quality inhering in a bearer by virtue of containing four homologous sets of chromosomes. ILX:0104986 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexapoda ILX:0104987 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexobarbital A barbiturate that is effective as a hypnotic and sedative. (PubChem) Pharmacology: Hexobarbital is a barbiturate derivative having hypnotic and sedative effects. It was used in the 1940s-1950s as an agent for inducing anesthesia for surgery and has a relatively fast onset of effects and short duration of action. However it can be difficult to control the depth of anesthesia with hexobarbital which makes it quite dangerous, and it has now been replaced by safer drugs in human medicine, usually thiopental would be the barbiturate of choice for this application these days. Mechanism of action: Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. Drug type: Approved. Small Molecule. Drug category: Adjuvants. Barbiturates. GABA Modulators. Hypnotics and Sedatives ILX:0104988 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
Hexylcaine Hexylcaine hydrochloride, also called cyclaine (Merck) or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function. Pharmacology: Hexylcaine is a local ester-class anesthetic. Local anesthetics produce a transient block of nerve conduction by interfering with sodium channels. This effect of the anesthetic interferes with the development of an action potential across the nerve. Mechanism of action: Hexyl caine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Drug type: Approved. Small Molecule. Drug category: Anesthetics. Local Anesthetics ILX:0104989 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High angular resolution diffusion imaging ILX:0104990 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High Angular Resolution Diffusion Imaging Protocol ILX:0104991 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High Bit Most significant bit for pixel sample data. Each sample shall have the same high bit. ILX:0104992 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High brightness Color brightness which is of high value. ILX:0104993 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High frequency recombinant A bacterial mating type that indicates the F plasmid has integrated into the chromosome. ILX:0104994 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High pass filter A filter that allows high frequencies to pass, stopping low frequencies. ILX:0104995 5 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High saturation Color saturation which is of high purity. ILX:0104996 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High voltage electron microscope transmission electron microscope cabable of operating an accelerating voltage in the range of 500- 1000 KeV ILX:0104997 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex NeuroLex
High-Dose Technique Type Type of high-dose treatment technique. ILX:0104998 6 FDI Lab - SciCrunch.org 08/28/2018 FDI Lab - SciCrunch.org term 12/08/2016 0 NeuroLex troy sincomb

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