Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD00991
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; Nulli 2 (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD00991 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD00232
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: pmr1-1/pmr1-1; Nulli 3 (IV)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD00232 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD02813
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hta1[∆::neo2]/hta1[∆::neo2; CHX!/CHX1; mpr1?/mpr1? (mp-r)
Affected Genes: HTA1 (TTHERM_00790790)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: HTA1 Germline knockout heterokaryon. Transformed CU428 X B2086 with pQR10B (removes all coding, replaces with neo cassette. It can mate with HTA1 G1 14B,
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02813 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD00878
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; pmr1-1/pmr1-1; Del 2L (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Deletion on left arm of chromosome 2.
Proper citation: RRID:TSC_SD00878 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD01846
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: CnjB/cnjB[∆?::neo3] (cnjB[∆?::neo3]
CnjB:neo3, fully assorted; pm-r)
Affected Genes: cnjB (TTHERM_01091290)
Genomic Alteration: Micronucleus: Part of CnjB coding replaced with neo3 Macronucleus: Part of CnjB coding replaced with neo3, completely assorted
Availability:
References:
Synonyms:
Notes: somatic knock-outs of CnjB obtained by mating heterozygous CnjB KO heterokaryon with WT then assorted to complete KO in mac; mate with ∆CnjB #1 and ∆CnjB #6
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD01846 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD01170
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; Nulli 2 (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD01170 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD03077
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: (V)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Collected by Paul Doerder on 6/1/2003 from the pond designated SG29 in PA (latitude 41.73, longitude -79.23)
Presence of micronucleus not determined.
Proper citation: RRID:TSC_SD03077 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD01174
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; pmr1-1/pmr1-1; Nulli 5 (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD01174 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD00122
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; mpr1-1/mpr1-1; cdaA/cdaA; Nulli 2L (CHX1; mpr1-1; cy-s, mp-r, tr, IV)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD00122 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD00763
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; pmr1-1/pmr1-1; Del 1L (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Deletion on left arm of chromosome 1.
Proper citation: RRID:TSC_SD00763 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD00367
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: Uni 3 [B or C3] (cnj3, pm-r, VII)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD00367 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD01614
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: rmm4[C3]/rmm4[C3]; mpr1-1/mpr1-1 (pmr1; mpr1-1; pm-r, mp-r, VI)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: rmm = rDNA maturation or maintenance mutation, located in the rDNA
Submitted by Eduardo Orias, University of California, Santa Barbara
Proper citation: RRID:TSC_SD01614 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD03082
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: (?)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Collected by Paul Doerder on 7/13/2006 from the pond designated Gregg Lake in NH (latitude 43.04, longitude -71.99)
Presence of micronucleus not determined. Mated with < 6 testers.
Proper citation: RRID:TSC_SD03082 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD02670
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mpr1-1/mpr1-1 (?HHT3/hht3[3’neo2,His-n]; pm-r, VII)
Affected Genes: HHT3 (TTHERM_00016170)
Genomic Alteration: Macronucleus: N-terminal His- tag of HHT3, not sure if complete replacement
Availability:
References:
Synonyms:
Notes: His-tagged hv2 transformant. Checked by western blot. His-hv2 is expressed.
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02670 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD02311
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hhf1[∆::neo1]/hhf1[∆::neo1]; hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2] (hht1[∆::neo2]; hht1[∆::neo2]; HHF2;
hht2[K9Q]; pm-r, ?)
Affected Genes: HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170)
Genomic Alteration: Micronucleus: Neo KO of all major HHT genes and HHF genes Macronucleus: WT HHF2 and mutated HHT2 with K9Q
Availability:
References:
Synonyms:
Notes: Germline heteokaryon Major H3 and H4 KO stains were mated and rescued with wt HHF2 gene/HHT2 gene with K9Q mutation.
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02311 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD01588
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: cdaC-1/cdaC-1; cdaF-1/cdaF-1 (cdaC-1; cdaF-1; cdaC, cdaF, II)
Affected Genes: CDAC (cell division arrest C), CDAF (cell division arrest F)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Joint expression of cdaC and cdaF patterns of fission arrest. The published phenotypic analysis was carried out in a sister clone that is no longer available.
Submitted by Joseph Frankel, University of Iowa
Proper citation: RRID:TSC_SD01588 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD02557
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hht3[∆::neo2]/hht3[∆::neo2];hht4[∆::bsr1]/hht4[∆::bsr1]
(hht3[∆::neo2];hht4[∆::bsr1]; pm-r, bsr-r, ?)
Affected Genes: HHT3 (TTHERM_00016170), HHT4 (TTHERM_00016200)
Genomic Alteration: Micronucleus: HHT3 KO with neo2, HHT4 KO with bsr1 Macronucleus: HHT3 KO with neo2, HHT4 KO with bsr1
Availability:
References:
Synonyms:
Notes: Homozygous homokaryon progeny of crossing ∆3N4B heterokaryons, C1nbe mated with ∆3N4B-2
This strain was stated to be pm-r, but proved not to be when thawed.
From the Gorovsky lab, University of Rochester.
Proper citation: RRID:TSC_SD02557 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD02833
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: DCR1/dcri[∆?::neo3] (DCR1; cy-r?, ?)
Affected Genes: DCR1 (TTHERM_01216140)
Genomic Alteration: Micronucleus: Nee3 cassette into DCR1 locus
Availability:
References:
Synonyms:
Notes: Heterozygous heterokaryon of DCR1 in B2086XCU427 background, can mate with SAI1 KO BXC7 1.0-1-2.
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02833 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD02556
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hht3[∆::neo2]/hht3[∆::neo2];hht4[∆::bsr1]/hht4[∆::bsr1]
(hht3[∆::neo2];hht4[∆::bsr1]; pm-r, bsr-r, ?)
Affected Genes: HHT3 (TTHERM_00016170), HHT4 (TTHERM_00016200)
Genomic Alteration: Micronucleus: HHT3 KO with neo2, HHT4 KO with bsr1 Macronucleus: HHT3 KO with neo2, HHT4 KO with bsr1
Availability:
References:
Synonyms:
Notes: Homozygous homokaryon progeny of crossing ∆3N4B heterokaryons, C1nbe mated with ∆3N4B-6
This strain was stated to be pm-r, but proved not to be when thawed.
From the Gorovsky lab, University of Rochester.
Proper citation: RRID:TSC_SD02556 Copy
https://tetrahymena.vet.cornell.edu/display.php?stockid=SD01745
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: cdaC-1/cdaC-1 (Originally published as mo3a) (cdaC-1; cdaC, III)
Affected Genes: CDAC (cell division arrest C) (originally published as mo3)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Located on chromosome 5. A sister clone of IA118, which expresses near complete fission blockage at temperatures of 39° C and 15°C (IA118 is reported in Dev. Biol. 58:255-275 but is extinct).
Submitted by Joseph Frankel, University of Iowa
Proper citation: RRID:TSC_SD01745 Copy
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