Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00000261
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004758(sek-1)|WBGene00006936(glp-4)
Genomic Alteration: WBGene00004758(sek-1), WBGene00006936(glp-4)
Availability: live
References:
Synonyms: glp-4(bn2) I; sek-1(km4) X.
Notes: Made_by: Terence Moy|"Temperature sensitive sterility. Maintain at 15C. Enhanced sensitivity to pathogens."|"WBStrain provided so WBPaper00061610 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00000261 Copy
http://www.wormbase.org/db/get?name=WBStrain00000259
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003822(nsy-1)
Genomic Alteration: WBGene00003822(nsy-1)
Availability: live
References:
Synonyms: nsy-1(ag3) II.
Notes: Enhanced susceptibility to pathogens (Esp). Nsy. Egl-d. Also called esp-8.|"WBStrain mapped, WBPaper00061439 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00000259 Copy
http://www.wormbase.org/db/get?name=WBStrain00000258
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004758(sek-1)
Genomic Alteration: WBGene00004758(sek-1)
Availability: live
References:
Synonyms: sek-1(ag1) X.
Notes: Enhanced susceptibility to pathogens (Esp). Egl-d. Nsy. Also called esp-2.
Proper citation: RRID:WB-STRAIN:WBStrain00000258 Copy
http://www.wormbase.org/db/get?name=WBStrain00000264
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: EMPTY
Genomic Alteration: EMPTY
Availability: live
References:
Synonyms: agIs17 IV.
Notes: agIs17 [myo-2p::mCherry + irg-1p::GFP] IV. GFP in pharynx and intestine that turns on upon infection with pathogenic Pseudomonas aeruginosa strain PA14. Reference: Dunbar TL, et al. Cell Host Microbe. 2012 Apr 19;11(4):375-86.|"WBStrain mapped, WBPaper00049531 added based on AFP_Strain data."|"WBStrain provided so WBPaper00059545 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061956 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00000264 Copy
http://www.wormbase.org/db/get?name=WBStrain00000281
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000499(chk-2)|WBGene00004399(rol-9)|WBGene00006786(unc-51)
Genomic Alteration: WBGene00000499(chk-2), WBGene00004399(rol-9), WBGene00006786(unc-51)
Availability: live
References:
Synonyms: chk-2(me64) rol-9(sc148)/unc-51(e369) rol-9(sc148) V.
Notes: Heterozygotes are fertile Rollers and segregate fertile non-Rollers (heterozygote), Unc Rollers (unc-51 homozygotes), and non-Unc Rollers that give 96-97% dead eggs (a high % of the survivors are males).
Proper citation: RRID:WB-STRAIN:WBStrain00000281 Copy
http://www.wormbase.org/db/get?name=WBStrain00000278
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003405(mre-11)
Genomic Alteration: WBGene00003405(mre-11)
Availability: live
References:
Synonyms: mre-11(ok179) IV/nT1 [unc-?(n754) let-?] (IV;V).
Notes: Heterozygotes are Unc and segregate Uncs (heterozygotes), non-Unc mre-11 homozygotes, and dead eggs (nT1 homozygotes). mre-11 homozygotes produce about 200 fertilized eggs but only about 2-3% of these eggs survive to adulthood (this mutation cannot be maintained in a homozygous condition). Occasionally non-Unc progeny that do not demonstrate the mre-11(ok179) mutant phenotype arise when grown in large liquid cultures. mre-11 is the predicted gene ZC302.1|"Made_by: Deletion Consortium"
Proper citation: RRID:WB-STRAIN:WBStrain00000278 Copy
http://www.wormbase.org/db/get?name=WBStrain00000290
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006375(syp-1)
Genomic Alteration: WBGene00006375(syp-1)
Availability: live
References:
Synonyms: syp-1(me17) V/nT1 [unc-?(n754) let-? qIs50] (IV;V).
Notes: Balanced heterozygotes are GFP+ Unc and segregate GFP+ Unc (heterozygotes), non-GFP non-Unc syp-1(me17) homozygotes, and dead eggs (nT1 homozygotes). syp-1(me17) homozygotes produce 95% dead embryos and 38% males. Cytologically they lack chiasmata in diakinesis-stage oocytes, exhibit persistent polarized nuclear organization during earlier meiotic prophase, lack synaptonemal complexes, and exhibit unstable pairing of homologous chromosomes. qIs50 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter (F22B7.9) driving GFP in the intestine.
Proper citation: RRID:WB-STRAIN:WBStrain00000290 Copy
http://www.wormbase.org/db/get?name=WBStrain00000001
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: EMPTY
Genomic Alteration: EMPTY
Availability: live
References:
Synonyms: Caenorhabditis elegans wild isolate.
Notes: C. elegans var Bristol. Generation time is about 3 days. Brood size is about 350. Also CGC reference 257. Isolated from mushroom compost near Bristol, England by L.N. Staniland. Cultured by W.L. Nicholas, identified to genus by Gunther Osche and species by Victor Nigon; subsequently cultured by C.E. Dougherty. Given to Sydney Brenner ca. 1966. Subcultured by Don Riddle in 1973. Caenorhabditis elegans wild isolate. DR subclone of CB original (Tc1 pattern I).|"C. elegans var Bristol. Generation time is about 3 days. Brood size is about 350. Also CGC reference 257. Isolated from mushroom compost near Bristol, England by L.N. Staniland. Cultured by W.L. Nicholas, identified to genus by Gunther Osche and species by Victor Nigon; subsequently cultured by C.E. Dougherty. Given to Sydney Brenner ca. 1966. Subcultured by Don Riddle in 1973. Caenorhabditis elegans wild isolate. DR subclone of CB original (Tc1 pattern I). [NOTE: This stock might carry a ~1.8 kb deletion in alh-2 in the background. (UPDATE: 03/26/2018 - a user reported the stock they received was homozygous for the alh-2(ot588) mutation.)]"|"C. elegans var Bristol. Generation time is about 3 days. Brood size is about 350. Also CGC reference 257. Isolated from mushroom compost near Bristol, England by L.N. Staniland. Cultured by W.L. Nicholas, identified to genus by Gunther Osche and species by Victor Nigon; subsequently cultured by C.E. Dougherty. Given to Sydney Brenner ca. 1966. Subcultured by Don Riddle in 1973. Caenorhabditis elegans wild isolate. DR subclone of CB original (Tc1 pattern I). [NOTE: This stock might carry a ~1.8 kb deletion in alh-2 in the background.]"|"Reference WBPaper00055815 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00056552 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00056729 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00056839 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00056884 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00056919 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00056921 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00057117 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00057197 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00057236 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00057259 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00057289 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00057312 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058621 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058626 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058640 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058667 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058717 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058750 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058810 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058832 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058851 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00059068 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00059172 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00059179 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00059256 added based on published strain data identified by Textpresso literature search."|"WT C. elegans. From Cambridge collection-originally frozen around 1968: In 1980, in order to establish an ancestral stock, Jonathan Hodgkin thawed one of the earliest frozen tubes of N2, dating from 1968. From this plate J.H. grew up a population en masse (without subculturing) on NGM plates (about 2 generations). Multiple samples of this were frozen in order to provide a reference N2 stock. This set of stock samples was replenished by regrowth in 1985 and 1991, using the same procedure, and a freshly thawed sample was sent to the CGC in 1993. Thus, samples from this frozen stock, called N2 (ancestral), should be only about 6 generations away from the stock used by Sydney Brenner as his standard WT N2. [Isolated from mushroom compost near Bristol, England by L.N. Staniland. Cultured by W.L. Nicholas, identified to genus by Gunther Osche and species by Victor Nigon; subsequently cultured by C.E. Dougherty. Given to Sydner Brenner ca. 1966.] Caenorhabditis elegans wild isolate. Note: N2 (ancestral) has reduced lifespan and fertility relative to the standard CGC N2 strains. See Worm Breeder's Gazette 16(5): 24 (February 1,2001)."
Proper citation: RRID:WB-STRAIN:WBStrain00000001 Copy
http://www.wormbase.org/db/get?name=WBStrain00000180
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006789(unc-54)
Genomic Alteration: WBGene00006789(unc-54)
Availability: live
References:
Synonyms: rmIs126.
Notes: Made_by: S. Garcia/A Chavez|"Mutagen:Gamma Rays"|"rmIs126 [unc-54p::Q0::YFP]. Diffuse distribution of Q0::YFP throughout the body-wall muscle cells. [NOTE: (04/29/13) Strain is reported as incorrect -- apparently carries 20Q transgene. Working on obtaining a replacement.]"
Proper citation: RRID:WB-STRAIN:WBStrain00000180 Copy
http://www.wormbase.org/db/get?name=WBStrain00031273
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004804(skn-1)
Genomic Alteration: WBGene00004804(skn-1)
Availability: live
References:
Synonyms: skn-1(zj15) IV.
Notes: Hypomorphic allele of skn-1 that may be propagated as a homozygote. High rate of embryonic lethality and slightly lower brood size compared to N2. Reference: Tang L, Dodd W, Choe K. G3 (Bethesda). 2015 Dec 29.|"Reference WBPaper00059755 added based on published strain data identified by Textpresso literature search."
Proper citation: RRID:WB-STRAIN:WBStrain00031273 Copy
http://www.wormbase.org/db/get?name=WBStrain00031361
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006406(srgp-1)
Genomic Alteration: WBGene00006406(srgp-1)
Availability: live
References:
Synonyms: srgp-1(ok300) IV.
Notes: F12F6.5. Homozygous. Outer Left Sequence: GATGTGAAGGCTGACAAGCA. Outer Right Sequence: TAACCCGTGCATTTGTTGAA. Inner Left Sequence: CTTCGAGGCCAATCATCAAT. Inner Right Sequence: GCCAAAACTATCATGGGCTG. Inner Primer PCR Length: 2904 bp. Deletion Size: 1406 bp. Deletion left flank: ttttattactttgttttatatttcaaaaac. Deletion right flank: atcaagtcgatcttcaaatcgatcaaaagc.|"Made_by: Vancouver KO Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00031361 Copy
http://www.wormbase.org/db/get?name=WBStrain00031400
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000195(arr-1)
Genomic Alteration: WBGene00000195(arr-1)
Availability: live
References:
Synonyms: arr-1(ok401) X.
Notes: F53H8.2. Homozygous. Outer Left Sequence: agttttatgccgctctcgaa. Outer Right Sequence: tcaattcgttccccactctc. Inner Left Sequence: caacttttccgccacataca. Inner Right Sequence: atggcggaagtttaccctct. Inner primer WT PCR product: 2402.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00031400 Copy
http://www.wormbase.org/db/get?name=WBStrain00031371
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003750(nlp-12)
Genomic Alteration: WBGene00003750(nlp-12)
Availability: live
References:
Synonyms: nlp-12(ok335) I.
Notes: M01D7.5. Superficially wild type.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."|"WBStrain mapped, WBPaper00060969 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061409 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061527 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00031371 Copy
http://www.wormbase.org/db/get?name=WBStrain00031350
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003970(pek-1)
Genomic Alteration: WBGene00003970(pek-1)
Availability: live
References:
Synonyms: pek-1(ok275) X.
Notes: F46C3.1. Homozygous. eukaryotic initiation factor 2 alpha kinase PEK. Outer Left Sequence: ctgagccatcgacaaactca. Outer Right Sequence: ccttggtaccattcaacgct. Inner Left Sequence: ctgagaaggcaacgctctct. Inner Right Sequence: atcaccgctactctggatgg. Inner primer WT PCR product: 2967.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."|"WBStrain mapped, WBPaper00060132 added based on AFP_Strain data."|"WBStrain provided so WBPaper00060933 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061805 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00031350 Copy
http://www.wormbase.org/db/get?name=WBStrain00031322
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001072(dpy-10)|WBGene00007433(swsn-7)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00007433(swsn-7)
Availability: live
References:
Synonyms: swsn-7(tm4263)/mIn1 [mIs14 dpy-10(e128)] II.
Notes: Heterozygotes are wild-type GFP+ that segregate wild-type GFP+ heterozygotes, GFP- tm4263 homozygotes (MEL), and Dpy GFP+ mIn1 homozygotes. Reference: Large EE and Mathies LD (2014 Jan 8). G3, doi: 10.1534/g3.113.009852.
Proper citation: RRID:WB-STRAIN:WBStrain00031322 Copy
http://www.wormbase.org/db/get?name=WBStrain00031485
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000222(atf-6)
Genomic Alteration: WBGene00000222(atf-6)
Availability: live
References:
Synonyms: atf-6(ok551) X.
Notes: F45E6.2. Homozygous. Outer Left Sequence: GGCGGGAGTTTAGGAGATTC. Outer Right Sequence: AAAGGCACGGAAATTGAGAA. Inner Left Sequence: AATGACCAGGAAATGTGGGA. Inner Right Sequence: AAGTGTCAATTGGCCAGTCC. Inner primer WT PCR product: 2983.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."|"WBStrain provided so WBPaper00060933 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00031485 Copy
http://www.wormbase.org/db/get?name=WBStrain00031408
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001501(ftn-2)
Genomic Alteration: WBGene00001501(ftn-2)
Availability: live
References:
Synonyms: ftn-2(ok404) I.
Notes: D1037.3. Homozygous. Ferritin. Outer Left Sequence: atctgcctgctttttgcact. Outer Right Sequence: agtttcgaatacgggtcgtg. Inner Left Sequence: gcaaacaaaaacgcttcgat. Inner Right Sequence: actggagctgcaatttgctt. Inner primer WT PCR product: 3129.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00031408 Copy
http://www.wormbase.org/db/get?name=WBStrain00031490
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001827(hcf-1)
Genomic Alteration: WBGene00001827(hcf-1)
Availability: live
References:
Synonyms: hcf-1(ok559) IV.
Notes: C46A5.9. Homozygous. Outer Left Sequence: tcatttcttgcagcaattcgctgttaacactgcgagagcg. Outer Right Sequence: . Inner Left Sequence: attcgaatcgatgatggagc. Inner Right Sequence: aaattgaagttgcaaacccg. Inner primer WT PCR product: 2512.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00031490 Copy
http://www.wormbase.org/db/get?name=WBStrain00031494
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004032(pkc-1)
Genomic Alteration: WBGene00004032(pkc-1)
Availability: live
References:
Synonyms: pkc-1(ok563) V.
Notes: F57F5.5. Homozygous. Outer Left Sequence: AAATTGTGAAACCGCACACA. Outer Right Sequence: TTGCAGCTATCCTGAACACG. Inner Left Sequence: TTCGGTAAGCCAAGTTGGAG. Inner Right Sequence: GGCGAGCAGTAGCACACATA. Inner primer WT PCR product: 2594.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00031494 Copy
http://www.wormbase.org/db/get?name=WBStrain00031413
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004109(stam-1)
Genomic Alteration: WBGene00004109(stam-1)
Availability: live
References:
Synonyms: stam-1(ok406) I.
Notes: C34G6.7. Homozygous. Outer Left Sequence: gctcaagagtgtggaggagg. Outer Right Sequence: gctcggaaaaatcactgctc. Inner Left Sequence: gattaatgggagaatgccga. Inner Right Sequence: ctgttgagaattgggaggga. Inner primer WT PCR product: 2799.|"Made_by: OMRF Knockout Group"|"Mutagen:UV/TMP"|"This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00031413 Copy
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