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http://digestivediseasescenters.org/content/ddrc-texas-medical-center-cellular-molecular-morphology-core

Core facility whose services include histology, immunohistochemistry, RNA in situ hybridization, mRNA probe generation, frozen sections for enzyme histochemistry, immunofluorescent antibody studies, live and fixed cell confocal, deconvolution microscopy and super resolution microscopy (SIM and STORM), and transmission electron microscopy, quantitative morphometric analysis, high throughput microscopy and high content analysis, laser capture microdissection for molecular genetic analyses, and digital images for internet communication and publication.

Proper citation: Texas Medical Center Digestive Diseases Center Cellular and Molecular Morphology Core (RRID:SCR_015219) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/study-design-and-clinical-research

Core that provides epidemiological and biostatistical support for design and analysis, and also provides investigators with access to the clinical specimens required for their basic and translational research activities. It offers assistance as well as didactic training in issues involving local and foreign IRB?s, HIPPA regulations, and importing or exporting clinical specimens.

Proper citation: Texas Medical Center Digestive Diseases Center Study Design and Clinical Research Core Services (RRID:SCR_015218) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/integrative-biology

Core that aims to provide turnkey access to organoids/enteroid technologies to TMC-DDC researchers. These include samples (enteroids, organoids), reagents (specialized growth media, etc.), training, and consultative expertise. The core also provides access to gnotobiotic facilities and animals, training and consultative expertise.

Proper citation: Texas Medical Center Digestive Diseases Center Integrative Biology Core (RRID:SCR_015220) Copy   

•   Source: SciCrunch Registry

http://cure.med.ucla.edu/cores/administrative

Management core that develops mission, goals, and strategies relating to the functioning of the CURE:DDRCC.

Proper citation: CURE - Digestive Diseases Research Center Administrative Core (RRID:SCR_015231) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/pluripotent-stem-cell

Core whose services include generation of human induced pluripotent stem cells (iPSCs) from DHC-relevant patient cells and directed differentiation of human pluripotent stem cells (hPSCs) to human intestinal organoids (HIOs).

Proper citation: Cincinnati Digestive Health Center Pluripotent Stem Cell and Organoid Core (RRID:SCR_015199) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/integrative-morphology

Core that provides pathology research service, live microscopy service, and confocal imaging to facilitate morphologic studies in digestive diseases.

Proper citation: Cincinnati Digestive Health Center Integrative Morphology (RRID:SCR_015197) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/gene-analysis

Core that provides Digestive Health Center (DHC) investigators technologies for gene and protein expression. The services provided by the Core are grouped into five types of technologies: Gene Expression Service, DNA Sequencing and Genotyping Core, Bioinformatics Service, Protein Expression-Research Flow Cytometry Core, and Protein Multiplexing-Luminex Assay.

Proper citation: Cincinnati Children's Hospital Digestive Health Center (RRID:SCR_015195) Copy   

•   Source: SciCrunch Registry

http://cure.med.ucla.edu/cores/morphology-and-imaging

Core facility which provides services through centralized resources and facilities, as well as training and assistance for the application of morphological, imaging and stem cell biology technologies and promoting collaborations among CURE:DDRCC investigators with independently-funded research projects.

Proper citation: CURE - Digestive Diseases Research Center Morphology and Imaging Core (RRID:SCR_015209) Copy   

•   Source: SciCrunch Registry

http://www.cure.med.ucla.edu/cores/human-studies

Core facility whose services include secretory tests, motility and pH tests, videoendoscopy, biopsy and histology, serum bank of patients with ulcer hemorrhage, and visceral sensitivity and autonomic function tests.

Proper citation: CURE - Digestive Diseases Research Center Human Studies Core (RRID:SCR_015207) Copy   

•   Source: SciCrunch Registry

https://case.edu/medicine/cddrcc/cores/

Collection of four cores: the biorepository core, for clinical specimen storage; the Histology/Imaging Core, for tissue preparation and sectioning; the Mouse Models Core, for education and training on various mouse modeling techniques; and the Clinical Component of the Administrative Core, for clinical study design consultation.

Proper citation: Cleveland Digestive Diseases Research Core Facilities (RRID:SCR_015216) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/functional-genomics-and-microbiome

Core whose services include consultation in the choice of genomics methodologies to be applied to research problems being addressed by Digestive Diseases Center members, training in the conduct of functional genomics and metagenomics relevant to GI research, providing mammalian gene expression, cytokine/transcription factor/signaling pathway arrays, and gut microbial profiling/metagenomics to DDC members at discounted prices, and conducting periodic workshops and disseminating information about new technologies available in the Core and to obtain feedback on needed technologies / services.

Proper citation: Texas Medical Center Digestive Diseases Center Functional Genomics and Microbiome (RRID:SCR_015214) Copy   

•   Source: SciCrunch Registry

https://ddrcc.wustl.edu/scientific-cores/murine-models-gnotobiotics-core/

Core facility that provides advice and technical services to DDRCC investigators that include production of transgenic and chimeric mice, derivation of speed congenics and assisted reproduction services for maintaining pedigrees via the Mouse Genetics Core, as well as gnotobiotic mouse provision, colonization and rederivation.

Proper citation: Washington University Digestive Diseases Research Core Center Murine Models and Gnotobiotics Core (RRID:SCR_015260) Copy   

•   Source: SciCrunch Registry

https://ww2.mc.vanderbilt.edu/DDRC/19909

Core facility whose services include training, acquisition and analysis on cytometers for experiments that include different fluorochromes, imaging cytometry, and mass cytometry.

Proper citation: Vanderbilt Digestive Disease Research Center Flow Cytometry Core (RRID:SCR_015251) Copy   

•   Source: SciCrunch Registry

https://ww2.mc.vanderbilt.edu/DDRC/6914

Core facility whose goals include furnishing professional guidance in experimental design and data interpretation and providing access to optical and electron microscopy. Its services include confocal microscopy, wide-field microscopy, transmission electron microscopy, and processing and embedment of tissue or cells for EM.

Proper citation: Vanderbilt Digestive Disease Research Center Cellular Imaging Core (RRID:SCR_015250) Copy   

•   Source: SciCrunch Registry

https://hddc.hms.harvard.edu/gnotobiotics-microbiology-and-metagenomics

Core facility that assists investigators evaluating host microbiota and its role in normal physiology and disease. It includes a number of resources for groups studying the role of the microbiota in human health and disease.

Proper citation: Harvard Digestive Diseases Center Biomedical CORE D: Gnotobiotic Mice, Microbiology and Metagenomics (RRID:SCR_012319) Copy   

•   Source: SciCrunch Registry

https://hddc.hms.harvard.edu/core-b

Core facility that provides service for paraffin embedding, sectioning, staining, and frozen sectioning; shared equipment and service for confocal, widefield, photodocumentation, electron microscopy, and digital image processing; and an immunostaining service.

Proper citation: Harvard Digestive Diseases Center Biomedical CORE B: Microscopy and Histopathology (RRID:SCR_009836) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/biostatistics

Core facility that provides comprehensive statistical and data management services. Its statistical analysis services include study design, power and sample size analysis, randomization, statistical programming, consultation and the development of analysis plans, graphs, figures and reports.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Biostatistics and Data Management Core (RRID:SCR_015616) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/histology

Core facility that provides a full range of histology services, encompassing routine and specialized grossing, tissue processing, paraffin embedding, microtomy, H&E and special staining, and immunohistochemistry. It also offers image analysis and consultations to CGIBD members and non-members.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Histology Core (RRID:SCR_015614) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/molecular/core_morphology.shtml

Core facility that provides histological services, equipment usage, and technical expertise to digestive and liver research projects.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Molecular Pathology and Imaging Core (RRID:SCR_015618) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/molecular/core_molecular.shtml

Core facility that provides services that will enhance the analysis of both host and microbial biological processes as well as facilitate translation into the clinical arena via human subject research.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Host-Microbial Analytic and Repository Core (RRID:SCR_015620) Copy   

•   Source: SciCrunch Registry