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Changes of Mycobacterium tuberculosis specific antigen-stimulated CD27-CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment.

European journal of medical research | 2024

The aim of the study was to investigate whether the expression of CD27-CD38+ in interferon (IFN)-γ+CD4+ T cells stimulated by the specific antigen early secreted antigenic target-6 (ESAT-6)/culture filter protein-10 (CFP-10) could be a potential new therapeutic evaluation indicator for anti-tuberculosis (TB) treatment.

Pubmed ID: 38429734 RIS Download

Research resources used in this publication

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Associated grants

  • Agency: Clinical study on the diagnostic value and efficacy evaluation of peripheral blood flow cytometry for tuberculosis,
    Id: fk18008
  • Agency: Clinical study on the diagnostic value and efficacy evaluation of peripheral blood flow cytometry for tuberculosis,
    Id: fk18008
  • Agency: Shanghai Clinical Research Center for infectious disease (tuberculosis),
    Id: 19MC1910800
  • Agency: Shanghai key clinical specialty construction project - Tuberculosis department,
    Id: Shslczdzc 03001
  • Agency: Shanghai 2020 "science and technology innovation action plan" technological innovation fund-Clinical Study on New Short-Course treatment regimens and Host-Directed Therapy for MDR-TB,
    Id: 20Z11900500

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FlowJo (tool)

RRID:SCR_008520

Software for single-cell flow cytometry analysis. Its functions include management, display, manipulation, analysis and publication of the data stream produced by flow and mass cytometers.

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