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Integrated single-nucleus sequencing and spatial architecture analysis identified distinct injured-proximal tubular types in calculi rats.

Cell & bioscience | 2023

Urolithiasis with high prevalence and recurrence rate, has impacts on kidney injury in patients, becomes a socioeconomic and healthcare problem in worldwide. However, the biology of kidney with crystal formation and proximal tubular injury remains essentially unclear. The present study aims to evaluate the cell biology and immune-communications in urolithiasis mediated kidney injury, to provide new insights in the kidney stone treatment and prevention.

Pubmed ID: 37208718 RIS Download

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Associated grants

  • Agency: Shenzhen Fundamental Research Program,
    Id: JCYJ20210324131414039
  • Agency: Scientific Research Projects of Medical and Health Institutions of Longhua District, Shenzhen,
    Id: Grant No. LHKJCXJCYJ202002, 2020003 and 2020013

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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