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Mechanisms and efficacy of metformin-mediated suppression of established experimental abdominal aortic aneurysms.

JVS-vascular science | 2023

Metformin treatment attenuates experimental abdominal aortic aneurysm (AAA) formation, as well as reduces clinical AAA diameter enlargement in patients with diabetes. The mechanisms of metformin-mediated aneurysm suppression, and its efficacy in suppressing established experimental aneurysms, remain uncertain.

Pubmed ID: 37168662 RIS Download

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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