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Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect.

Annals of the rheumatic diseases | 2023

Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is unclear if EHOA is genetically different from other forms of OA. Sequence variants at ten loci have been associated with hand OA but none with EHOA.

Pubmed ID: 36931692 RIS Download

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UK Biobank (tool)

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Biobank provides data collected at Assessment Center and via online questionnaires on participants aged 40-69 years recruited throughout United Kingdom and provides summary information to improve prevention, diagnosis and treatment of serious and life threatening illnesses.

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Open Targets Genetics Portal (tool)

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Portal offers features to help discover associations between genes, variants, and traits including Browse and rank gene and variant associations identified by Locus-to-Gene (L2G) scoring pipeline, Uncover credible sets for variant and trait associations based on mapping analyses pipeline, Explore and compare studies from UK Biobank, FinnGen, and GWAS Catalog using multi-trait comparison tool eQTL Catalogue.

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