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Kai-Xin-San protects against mitochondrial dysfunction in Alzheimer's disease through SIRT3/NLRP3 pathway.

Chinese medicine | 2023

Kai-Xin-San (KXS) has been reported to have a good curative impact on dementia. The purpose of the study was to determine whether KXS might ameliorate cognitive deficits in APP/PS1 mice and to evaluate its neuroprotective mechanism.

Pubmed ID: 36918872 RIS Download

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Associated grants

  • Agency: National Natural Science Foundation of China,
    Id: No.81973918
  • Agency: Guangdong Province Science and Technology Plan International Cooperation Project,
    Id: No. 2020A0505100052

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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HT22 (tool)

RRID:CVCL_0321

Cell line HT22 is a Transformed cell line with a species of origin Mus musculus (Mouse)

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B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax (organism)

RRID:MMRRC_034829-JAX

Mus musculus with name B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax from MMRRC.

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