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Episodic Memory, Hippocampal Volume, and Function for Classification of Mild Cognitive Impairment Patients Regarding Amyloid Pathology.

Journal of Alzheimer's disease : JAD | 2022

Previous studies of hippocampal function and volume related to episodic memory deficits in patients with amnestic mild cognitive impairment (aMCI) have produced mixed results including increased or decreased activity and volume. However, most of them have not included biomarkers, such as amyloid-β (Aβ) deposition which is the hallmark for early identification of the Alzheimer's disease continuum.

Pubmed ID: 35871330 RIS Download

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This is a list of tools and resources that we have found mentioned in this publication.


FreeSurfer (tool)

RRID:SCR_001847

Open source software suite for processing and analyzing human brain MRI images. Used for reconstruction of brain cortical surface from structural MRI data, and overlay of functional MRI data onto reconstructed surface. Contains automatic structural imaging stream for processing cross sectional and longitudinal data. Provides anatomical analysis tools, including: representation of cortical surface between white and gray matter, representation of the pial surface, segmentation of white matter from rest of brain, skull stripping, B1 bias field correction, nonlinear registration of cortical surface of individual with stereotaxic atlas, labeling of regions of cortical surface, statistical analysis of group morphometry differences, and labeling of subcortical brain structures.Operating System: Linux, macOS.

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Geriatric Depression Scale (tool)

RRID:SCR_008739

A basic screening measure for depression in older adults. They have a FREE iPhone APP and a FREE ANDROID APP that allows you to do the 15-item GDS on your phone and automatically calculate the results. They provide no interpretation of results, but patients with scores higher than 5 should be interviewed carefully. These apps are also available through the Android Marketplace or iTunes stores on your phones. Note: This page is under continuous development but they will try to keep translations of the scale available. Anyone with their own translation can submit it and they''ll post it.

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Neuroimaging in Python (tool)

RRID:SCR_013141

Community site to make brain imaging research easier that aims to build software that is clearly written, clearly explained, a good fit for the underlying ideas, and a natural home for collaboration.

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Artifact Detection Tools (software resource)

RRID:SCR_005994

Toolbox for post-processing fMRI data. Includes software for comprehensive analysis of sources of artifacts in timeseries data including spiking and motion. Most compatible with SPM processing, but adaptable for FSL as well. * Operating System: MacOS, Windows, Linux * Programming Language: MATLAB * Supported Data Format: ANALYZE

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