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Medulloblastoma is the most frequent brain malignancy of childhood. The current multimodal treatment comes at the expense of serious and often long-lasting side effects. Drug repurposing is a strategy to fast-track anti-cancer therapy with low toxicity. Here, we showed the ability of β-blockers to potentiate radiotherapy in medulloblastoma with bad prognosis.
Pubmed ID: 35816899 RIS Download
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Global nonprofit biological resource center (BRC) and research organization that provides biological products, technical services and educational programs to private industry, government and academic organizations. Its mission is to acquire, authenticate, preserve, develop and distribute biological materials, information, technology, intellectual property and standards for the advancement and application of scientific knowledge. The primary purpose of ATCC is to use its resources and experience as a BRC to become the world leader in standard biological reference materials management, intellectual property resource management and translational research as applied to biomaterial development, standardization and certification. ATCC characterizes cell lines, bacteria, viruses, fungi and protozoa, as well as develops and evaluates assays and techniques for validating research resources and preserving and distributing biological materials to the public and private sector research communities.
View all literature mentionsSoftware performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays.
View all literature mentionsSoftware ultrafast memory efficient tool for aligning sequencing reads. Bowtie is short read aligner.
View all literature mentionsSoftware repository for R packages related to analysis and comprehension of high throughput genomic data. Uses separate set of commands for installation of packages. Software project based on R programming language that provides tools for analysis and comprehension of high throughput genomic data.
View all literature mentionsAmerican chemical, life science and biotechnology company owned by Merck KGaA. Merger of Sigma Chemical Company and Aldrich Chemical Company. Provides organic and inorganic chemicals, building blocks, reagents, advanced materials and stable isotopes for chemical synthesis, medicinal chemistry and materials science, antibiotics, buffers, carbohydrates, enzymes, forensic tools, hematology and histology, nucleotides, proteins, peptides, amino acids and their derivatives.
View all literature mentionsSoftware tool that removes adapter sequences from DNA sequencing reads.
View all literature mentionsAn Antibody supplier; Dako was purchased by Agilent in 2012 and several years later the websites began to reflect the Dako products as part of the Agilent catalog.
View all literature mentionsSoftware package for differential gene expression analysis based on the negative binomial distribution. Used for analyzing RNA-seq data for differential analysis of count data, using shrinkage estimation for dispersions and fold changes to improve stability and interpretability of estimates.
View all literature mentionsTHIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 15,2023. High-throughput sequencing system. High-quality data using proven Illumina SBS chemistry has made it the instrument of choice for major genome centers and research institutions throughout the world.HiSeq 2500 System has been discontinued. Illumina will support the instrument and intends to supply the reagents through February 28, 2023.
View all literature mentionsLightCycler 480 Instrument is a real-time PCR device, allowing the use of additional thermal block cycler units (96-well and 384-well format) with the system. The LightCycler 480 Block Kit 384 Silver comprises a block cycler unit for 384-well PCR plates, a corresponding block lid for the 384-well PCR plates, and a storage box for both accessories.
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
View all literature mentionsThis polyclonal secondary targets IgG
View all literature mentionsThis recombinant monoclonal targets Cox2
View all literature mentionsThis polyclonal targets Ki67 antibody - Proliferation Marker
View all literature mentionsStatistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
View all literature mentionsTHIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 15,2023. High-throughput sequencing system. High-quality data using proven Illumina SBS chemistry has made it the instrument of choice for major genome centers and research institutions throughout the world.HiSeq 2500 System has been discontinued. Illumina will support the instrument and intends to supply the reagents through February 28, 2023.
View all literature mentionsSequencer that uses patterned flow cell technology to provide high-performance sequencing. Perform production-scale, high-throughput exome or transcriptome sequencing projects quickly and economically.
View all literature mentionsLightCycler 480 Instrument is a real-time PCR device, allowing the use of additional thermal block cycler units (96-well and 384-well format) with the system. The LightCycler 480 Block Kit 384 Silver comprises a block cycler unit for 384-well PCR plates, a corresponding block lid for the 384-well PCR plates, and a storage box for both accessories.
View all literature mentionsSeahorse XFe24 Analyzers measure OCR and ECAR of live cells in a 24-well plate format.
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsImmunohistochemistry processor that can be used for immunohistochemistry and in situ hybridization slide preparation and processing.
View all literature mentionsProcessor that automatically washes tissue sample which needs to be usable in downstream processes. Designed for routine and research histopathology of up to 300 cassettes.
View all literature mentionsVibrating blade microtome for sectioning by Leica Biosystems. Used in neurophysiology, neuropathology, experimental pathology, botany (roots and plants) and industry (foams).
View all literature mentionsCell line HD-MB03 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsIncuCyte ZOOM system is a live-cell imaging and analysis platform that enables automated quantification of cell behavior over time (from hours to weeks) by automatically gathering and analyzing images around the clock. The system provides insight into active biological processes in real-time which is not possible using single-point and end-point measurements. The system resides within the controlled environment of a standard cell incubator. All imaging is completely non-invasive and non-perturbing to cell health. The system can process multiple plates, flasks and dishes in parallel and does not depend on shuttling plates into and out of the incubator.
View all literature mentionslaboratory mouse with name nude from MGI.
View all literature mentionslaboratory mouse with name C57BL/6 from MGI.
View all literature mentionsCell line ONS-76 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line D283 Med is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line Daoy is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsThe SciCrunch Infrastructure was developed as a cooperative data platform to be used by diverse communities in making data more FAIR.
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