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Synthesis of a 2-nitroimidazole derivative N-(4-[18F]fluorobenzyl)-2-(2-nitro-1H-imidazol-1-yl)-acetamide ([18 F]FBNA) as PET radiotracer for imaging tumor hypoxia.

EJNMMI radiopharmacy and chemistry | 2022

Tissue hypoxia is a pathological condition characterized by reducing oxygen supply. Hypoxia is a hallmark of tumor environment and is commonly observed in many solid tumors. Non-invasive imaging techniques like positron emission tomography (PET) are at the forefront of detecting and monitoring tissue hypoxia changes in vivo.

Pubmed ID: 35697954 RIS Download

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Associated grants

  • Agency: Fundação de Amparo à Pesquisa do Estado de São Paulo,
    Id: 2012/06875-6
  • Agency: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,
    Id: 142180/2015-7
  • Agency: Government of Canada,
    Id: ELAP 2017-2018

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MKN45 (tool)

RRID:CVCL_0434

Cell line MKN45 is a Cancer cell line with a species of origin Homo sapiens (Human)

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