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Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies.

Journal of clinical immunology | 2022

Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for early identification of IFN-AAB-positive patients for potential subsequent clinical interventions.

Pubmed ID: 35511314 RIS Download

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Associated grants

  • Agency: NIAID NIH HHS, United States
    Id: HHSN272201400008C

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ClinicalTrials.gov (tool)

RRID:SCR_002309

Registry and results database of federally and privately supported clinical trials conducted in United States and around world. Provides information about purpose of trial, who may participate, locations, and phone numbers for more details. This information should be used in conjunction with advice from health care professionals.Offers information for locating federally and privately supported clinical trials for wide range of diseases and conditions. Research study in human volunteers to answer specific health questions. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings. ClinicalTrials.gov contains trials sponsored by National Institutes of Health, other federal agencies, and private industry. Studies listed in database are conducted in all 50 States and in 178 countries.

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PeproTech (tool)

RRID:SCR_006802

An Antibody supplier

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Calu-3 (tool)

RRID:CVCL_0609

Cell line Calu-3 is a Cancer cell line with a species of origin Homo sapiens (Human)

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