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Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets.

Gastroenterology | 2022

Polygenic and environmental factors are underlying causes of inflammatory bowel disease (IBD). We hypothesized that integration of the genetic loci controlling a metabolite's abundance, with known IBD genetic susceptibility loci, may help resolve metabolic drivers of IBD.

Pubmed ID: 34780722 RIS Download

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: K23 DK129762
  • Agency: NIDDK NIH HHS, United States
    Id: RC2 DK122532
  • Agency: NIH HHS, United States
    Id: S10 OD026880
  • Agency: NIH HHS, United States
    Id: S10 OD030463

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HEK293 (tool)

RRID:CVCL_0045

Cell line HEK293 is a Transformed cell line with a species of origin Homo sapiens (Human)

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