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Anatomical structures, cell types and biomarkers of the Human Reference Atlas.

Nature cell biology | 2021

The Human Reference Atlas (HRA) aims to map all of the cells of the human body to advance biomedical research and clinical practice. This Perspective presents collaborative work by members of 16 international consortia on two essential and interlinked parts of the HRA: (1) three-dimensional representations of anatomy that are linked to (2) tables that name and interlink major anatomical structures, cell types, plus biomarkers (ASCT+B). We discuss four examples that demonstrate the practical utility of the HRA.

Pubmed ID: 34750582 RIS Download

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Associated grants

  • Agency: NIH HHS, United States
    Id: OT2 OD026671
  • Agency: NIAMS NIH HHS, United States
    Id: U54 AR081775
  • Agency: NLM NIH HHS, United States
    Id: R01 LM012832
  • Agency: NIDDK NIH HHS, United States
    Id: U01 DK107350
  • Agency: NCI NIH HHS, United States
    Id: UH3 CA246594

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SPARC Project (storage service resource)

RRID:SCR_017041

The SPARC data repository as of 2023 is an open data repository developed as part of the NIH SPARC initiative and has been used by SPARC funded investigator groups to curate and publish high quality datasets related to the autonomic nervous system. We are thrilled that as of August 2022, SPARC is accepting datasets from investigators that are not funded through the NIH SPARC program. The NIH's Common Fund Stimulating Peripheral Activity to Relieve Conditions (SPARC) program aims to transform our understanding of these nerve-organ interactions and ultimately advance neuromodulation field toward precise treatment of diseases and conditions for which conventional therapies fall short.

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