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Comparison of HER2-Targeted Antibodies for Fluorescence-Guided Surgery in Breast Cancer.

Molecular imaging | 2021

Although therapeutic advances have led to enhanced survival in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer, detection of residual disease remains challenging. Here, we examine two approved anti-HER2 monoclonal antibodies (mAbs), trastuzumab and pertuzumab, as potential candidates for the development of immunoconjugates for fluorescence-guided surgery (FGS).

Pubmed ID: 34194285 RIS Download

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