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Spatial concordance of DNA methylation classification in diffuse glioma.

Neuro-oncology | 2021

Intratumoral heterogeneity is a hallmark of diffuse gliomas. DNA methylation profiling is an emerging approach in the clinical classification of brain tumors. The goal of this study is to investigate the effects of intratumoral heterogeneity on classification confidence.

Pubmed ID: 34049406 RIS Download

Research resources used in this publication

None found

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Antibodies used in this publication

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: P50 CA097257
  • Agency: NCI NIH HHS, United States
    Id: R01 CA237208
  • Agency: NCI NIH HHS, United States
    Id: R01 CA190121
  • Agency: NINDS NIH HHS, United States
    Id: R21 NS114873
  • Agency: NCI NIH HHS, United States
    Id: R01 CA244838
  • Agency: NCI NIH HHS, United States
    Id: P30 CA034196
  • Agency: NCI NIH HHS, United States
    Id: K99 CA226387

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This is a list of tools and resources that we have found mentioned in this publication.


wateRmelon (tool)

RRID:SCR_001296

Software package for Illumina 450 methylation array normalization and metrics including 15 flavors of betas and three performance metrics, with methods for objects produced by methylumi, minfi and IMA packages.

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FISHER (tool)

RRID:SCR_009181

THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 1st, 2022. Software application for genetic analysis of classical biometric traits like blood pressure or height that are caused by a combination of polygenic inheritance and complex environmental forces. (entry from Genetic Analysis Software)

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