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Adenylate kinase 1 (AK1) catalyses the reaction 2ADP ↔ ATP + AMP, extracting extra energy under metabolic stress and promoting energetic homeostasis. We hypothesised that increased AK1 activity would have negligible effects at rest, but protect against ischaemia/reperfusion (I/R) injury.
Pubmed ID: 33867998 RIS Download
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laboratory mouse with name C57BL/6JOlaHsd from MGI.
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