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Inactivation of Cys674 (C674) in the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) causes intracellular Ca2+ accumulation, which activates calcineurin-mediated nuclear factor of activated T-lymphocytes (NFAT)/NF-κB pathways, and results in the phenotypic modulation of smooth muscle cells (SMCs) to accelerate angiotensin II-induced aortic aneurysms. Our goal was to investigate the mechanism involved.
Pubmed ID: 33591571 RIS Download
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This unknown targets
View all literature mentionsThis polyclonal targets IgG-Fc
View all literature mentionsThis polyclonal targets GAPDH
View all literature mentionsThis polyclonal targets NFAT4 antibody
View all literature mentionsThis polyclonal targets icam1
View all literature mentionsThis polyclonal targets VCAM
View all literature mentionsThis polyclonal targets NFκB-p65
View all literature mentionsThis polyclonal targets Collagen III
View all literature mentionsThis polyclonal targets Collagen I
View all literature mentionsThis polyclonal targets Osteopontin
View all literature mentionsThis polyclonal targets Myocardin antibody
View all literature mentionsStatistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
View all literature mentionsSoftware suite for image acquisition and analysis. The software can be paired with high-quality cameras to maximize output quality and export it for sharing and research applications.
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsTHIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression.
View all literature mentionsTHIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software Python package that provides infrastructure to process data from high-throughput sequencing assays. While the main purpose of HTSeq is to allow you to write your own analysis scripts, customized to your needs, there are also a couple of stand-alone scripts for common tasks that can be used without any Python knowledge.
View all literature mentionsCollection of genome databases for vertebrates and other eukaryotic species with DNA and protein sequence search capabilities. Used to automatically annotate genome, integrate this annotation with other available biological data and make data publicly available via web. Ensembl tools include BLAST, BLAT, BioMart and the Variant Effect Predictor (VEP) for all supported species.
View all literature mentionsMus musculus with name B6.129S7-Ldlrtm1Her/J from IMSR.
View all literature mentionslaboratory mouse with name C57BL/6J-Atp2a2tm1.1Raco/Raco from MGI.
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
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