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High expression of BCL6 inhibits the differentiation and development of hematopoietic stem cells and affects the growth and development of chickens.

Journal of animal science and biotechnology | 2021

B-cell CLL/lymphoma 6 (BCL6) is a transcriptional master regulator that represses more than 1200 potential target genes. Our previous study showed that a decline in blood production in runting and stunting syndrome (RSS) affected sex-linked dwarf (SLD) chickens compared to SLD chickens. However, the association between BCL6 gene and hematopoietic function remains unknown in chickens.

Pubmed ID: 33541426 RIS Download

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