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Diminished Learning Over Repeated Exposures (LORE) in preclinical Alzheimer's disease.

Alzheimer's & dementia (Amsterdam, Netherlands) | 2020

We determine whether diminished Learning Over Repeated Exposures (LORE) identifies subtle memory decrements in cognitively unimpaired (CU) older adults with Alzheimer's disease (AD) biomarker burden.

Pubmed ID: 33426266 RIS Download

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Associated grants

  • Agency: NIA NIH HHS, United States
    Id: K23 AG053422
  • Agency: NIA NIH HHS, United States
    Id: K24 AG035007
  • Agency: NIA NIH HHS, United States
    Id: P01 AG036694

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FreeSurfer (tool)

RRID:SCR_001847

Open source software suite for processing and analyzing human brain MRI images. Used for reconstruction of brain cortical surface from structural MRI data, and overlay of functional MRI data onto reconstructed surface. Contains automatic structural imaging stream for processing cross sectional and longitudinal data. Provides anatomical analysis tools, including: representation of cortical surface between white and gray matter, representation of the pial surface, segmentation of white matter from rest of brain, skull stripping, B1 bias field correction, nonlinear registration of cortical surface of individual with stereotaxic atlas, labeling of regions of cortical surface, statistical analysis of group morphometry differences, and labeling of subcortical brain structures.Operating System: Linux, macOS.

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