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Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis.

Arthritis research & therapy | 2020

Antibodies binding to cartilage proteins are present in the blood and synovial fluid of early rheumatoid arthritis patients. In order to develop animal models mimicking the human disease, we have characterized the arthritogenic capacity of monoclonal antibodies directed towards different joint proteins in the cartilage.

Pubmed ID: 32448385 RIS Download

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GraphPad Prism (tool)

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