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Metabolomic analysis of serum and myocardium in compensated heart failure after myocardial infarction.

Life sciences | 2019

To determine the metabolic adaptations to compensated heart failure using a reproducible model of myocardial infarction and an unbiased metabolic screen. To address the limitations in sample availability and model variability observed in preclinical and clinical metabolic investigations of heart failure.

Pubmed ID: 30731143 RIS Download

Research resources used in this publication

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: R42 HL122038
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL107200
  • Agency: BLRD VA, United States
    Id: I01 BX001963
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL091071
  • Agency: BLRD VA, United States
    Id: I01 BX001515
  • Agency: BLRD VA, United States
    Id: I01 BX003774
  • Agency: BLRD VA, United States
    Id: I01 BX000783
  • Agency: NHLBI NIH HHS, United States
    Id: P01 HL066941

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Cytoscape (tool)

RRID:SCR_003032

Software platform for complex network analysis and visualization. Used for visualization of molecular interaction networks and biological pathways and integrating these networks with annotations, gene expression profiles and other state data.

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Sigma-Aldrich (tool)

RRID:SCR_008988

American chemical, life science and biotechnology company owned by Merck KGaA. Merger of Sigma Chemical Company and Aldrich Chemical Company. Provides organic and inorganic chemicals, building blocks, reagents, advanced materials and stable isotopes for chemical synthesis, medicinal chemistry and materials science, antibiotics, buffers, carbohydrates, enzymes, forensic tools, hematology and histology, nucleotides, proteins, peptides, amino acids and their derivatives.

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