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Transgelin as a potential target in the reversibility of pulmonary arterial hypertension secondary to congenital heart disease.

Journal of cellular and molecular medicine | 2018

The reversibility of pulmonary arterial hypertension (PAH) in congenital heart disease (CHD) is of great importance for the operability of CHD. Proteomics analysis found that transgelin was significantly up-regulated in the lung tissue of CHD-PAH patients, especially in the irreversible group. However, how exactly it participated in CHD-PAH development is unknown.

Pubmed ID: 30338626 RIS Download

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Software tool for protein identification and relative protein expression analysis. Used in protein research to identify proteins and search large numbers of post translational modifications. Compatible with all proteomics MS/MS systems.

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