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TRIM52 up-regulation in hepatocellular carcinoma cells promotes proliferation, migration and invasion through the ubiquitination of PPM1A.

Journal of experimental & clinical cancer research : CR | 2018

Many tripartite motif (TRIM) family proteins have been reported to be of great importance in the initiation and progression in hepatocellular carcinoma (HCC). However, the biological role and regulatory mechanism of tripartite motif containing 52 (TRIM52) in HCC development and progression are poorly defined.

Pubmed ID: 29898761 RIS Download

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Associated grants

  • Agency: National Natural Science Foundation of China,
    Id: 81770589
  • Agency: Natural Science Foundation of Shanghai,
    Id: 17ZR1421500
  • Agency: Scientific Research Fund of Shanghai Municipal Health and Family Planning Commission for Traditional Chinese Medicine,
    Id: 2014JQ019A
  • Agency: Medical Education Research Project of Shanghai Jiao Tong University School of Medicine,
    Id: YB150712

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HEK293T (tool)

RRID:CVCL_0063

Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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MHCC97-L (tool)

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Cell line MHCC97-L is a Cancer cell line with a species of origin Homo sapiens (Human)

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MHCC97-H (tool)

RRID:CVCL_4972

Cell line MHCC97-H is a Cancer cell line with a species of origin Homo sapiens (Human)

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