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The presence of human mesenchymal stem cells of renal origin in amniotic fluid increases with gestational time.

Stem cell research & therapy | 2018

Established therapies for managing kidney dysfunction such as kidney dialysis and transplantation are limited due to the shortage of compatible donated organs and high costs. Stem cell-based therapies are currently under investigation as an alternative treatment option. As amniotic fluid is composed of fetal urine harboring mesenchymal stem cells (AF-MSCs), we hypothesized that third-trimester amniotic fluid could be a novel source of renal progenitor and differentiated cells.

Pubmed ID: 29695308 RIS Download

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Associated grants

  • Agency: Deutscher Akademischer Austauschdienst, International
    Id: 91607303

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DAVID (tool)

RRID:SCR_001881

Bioinformatics resource system including web server and web service for functional annotation and enrichment analyses of gene lists. Consists of comprehensive knowledgebase and set of functional analysis tools. Includes gene centered database integrating heterogeneous gene annotation resources to facilitate high throughput gene functional analysis.

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affy (tool)

RRID:SCR_012835

Software R package of functions and classes for the analysis of oligonucleotide arrays manufactured by Affymetrix. Used to process probe level data and for exploratory oligonucleotide array analysis.

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HFF-1 (tool)

RRID:CVCL_3285

Cell line HFF-1 is a Finite cell line with a species of origin Homo sapiens (Human)

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