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Probing Glioblastoma Tissue Heterogeneity with Laser Capture Microdissection.

Methods in molecular biology (Clifton, N.J.) | 2018

Among various methods now available to isolate distinct cell populations or even single cells for DNA/RNA and proteomic analysis, laser capture microdissection (LCM) offers a unique opportunity to study cells in their topological contexts. This chapter focuses on the preparation of LCM membrane slides, tissue staining and laser microdissection of cells of interest from frozen or formalin-fixed, paraffin-embedded glioblastoma tissue.

Pubmed ID: 29392703 RIS Download

Research resources used in this publication

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Associated grants

  • Agency: NINDS NIH HHS, United States
    Id: R21 NS074055
  • Agency: NCI NIH HHS, United States
    Id: P30 CA016087

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New York University School of Medicine Langone Health Microscopy Laboratory Core Facility (tool)

RRID:SCR_017934

Core offers comprehensive light and electron microscopy technologies. Our scientists use light microscopes and electron microscopes at resolutions ranging from centimeters to angstroms, providing clear and detailed images.We assist at every stage of your experiment, offering research-design consultation and instrument training, as well as guidance in study execution, analysis, and presentation for publication.

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