Actinic Keratosis (AK), is the most common precancerous skin lesion induced by the excessive Ultraviolet B (UVB) and is a significant threat to the public health. UVB exposure causes oxidative DNA damage and is considered to be a significant contributor to AK and subsequent development of skin cancer. Besides, activation of p38 MAPK also plays a significant role in the development of AK.
Pubmed ID: 29298652 RIS Download
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Cell line HaCaT is a Spontaneously immortalized cell line with a species of origin Homo sapiens (Human)
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