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Interleukin-6 upregulates SOX18 expression in osteosarcoma.

OncoTargets and therapy | 2017

SOX18 is a potential oncogene in osteosarcoma via controlling osteosarcoma cell proliferation and metastasis. Interleukin-6 (IL-6), a major activator of Janus kinase 2 (JAK2)/signal transducers and activators of transcription 3 (STAT3) signaling, plays an important role in the growth of carcinoma cells. The present study aims to investigate the correlation between IL-6 and SOX18 in osteosarcoma.

Pubmed ID: 29184419 RIS Download

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