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Effector CD8+ T cell-derived interleukin-10 enhances acute liver immunopathology.

Journal of hepatology | 2017

Besides secreting pro-inflammatory cytokines, chemokines and effector molecules, effector CD8+ T cells that arise upon acute infection with certain viruses have been shown to produce the regulatory cytokine interleukin (IL)-10 and, therefore, contain immunopathology. Whether the same occurs during acute hepatitis B virus (HBV) infection and role that IL-10 might play in liver disease is currently unknown.

Pubmed ID: 28483675 RIS Download

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