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Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Vijay Ramaswamy | Thomas Hielscher | Stephen C Mack | Alvaro Lassaletta | Tong Lin | Kristian W Pajtler | David T W Jones | Betty Luu | Florence M G Cavalli | Kenneth Aldape | Marc Remke | Martin Mynarek | Stefan Rutkowski | Sridharan Gururangan | Roger E McLendon | Eric S Lipp | Christopher Dunham | Juliette Hukin | David D Eisenstat | Dorcas Fulton | Frank K H van Landeghem | Mariarita Santi | Marie-Lise C van Veelen | Erwin G Van Meir | Satoru Osuka | Xing Fan | Karin M Muraszko | Daniela P C Tirapelli | Sueli M Oba-Shinjo | Suely K N Marie | Carlos G Carlotti | Ji Yeoun Lee | Amulya A Nageswara Rao | Caterina Giannini | Claudia C Faria | Sofia Nunes | Jaume Mora | Ronald L Hamilton | Peter Hauser | Nada Jabado | Kevin Petrecca | Shin Jung | Luca Massimi | Massimo Zollo | Giuseppe Cinalli | László Bognár | Almos Klekner | Tibor Hortobágyi | Sarah Leary | Ralph P Ermoian | James M Olson | Jeffrey R Leonard | Corrine Gardner | Wieslawa A Grajkowska | Lola B Chambless | Jason Cain | Charles G Eberhart | Sama Ahsan | Maura Massimino | Felice Giangaspero | Francesca R Buttarelli | Roger J Packer | Lyndsey Emery | William H Yong | Horacio Soto | Linda M Liau | Richard Everson | Andrew Grossbach | Tarek Shalaby | Michael Grotzer | Matthias A Karajannis | David Zagzag | Helen Wheeler | Katja von Hoff | Marta M Alonso | Teresa Tuñon | Ulrich Schüller | Karel Zitterbart | Jaroslav Sterba | Jennifer A Chan | Miguel Guzman | Samer K Elbabaa | Howard Colman | Girish Dhall | Paul G Fisher | Maryam Fouladi | Amar Gajjar | Stewart Goldman | Eugene Hwang | Marcel Kool | Harshad Ladha | Elizabeth Vera-Bolanos | Khalida Wani | Frank Lieberman | Tom Mikkelsen | Antonio M Omuro | Ian F Pollack | Michael Prados | H Ian Robins | Riccardo Soffietti | Jing Wu | Phillipe Metellus | Uri Tabori | Ute Bartels | Eric Bouffet | Cynthia E Hawkins | James T Rutka | Peter Dirks | Stefan M Pfister | Thomas E Merchant | Mark R Gilbert | Terri S Armstrong | Andrey Korshunov | David W Ellison | Michael D Taylor
Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 2016

Posterior fossa ependymoma comprises two distinct molecular variants termed EPN_PFA and EPN_PFB that have a distinct biology and natural history. The therapeutic value of cytoreductive surgery and radiation therapy for posterior fossa ependymoma after accounting for molecular subgroup is not known.

Pubmed ID: 27269943 RIS Download

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: P30 CA016087
  • Agency: NCI NIH HHS, United States
    Id: R01 CA159859
  • Agency: Canadian Institutes of Health Research, International
  • Agency: NINDS NIH HHS, United States
    Id: R25 NS079198
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS096236
  • Agency: NCI NIH HHS, United States
    Id: R01 CA163737
  • Agency: NCI NIH HHS, United States
    Id: R01 CA148621
  • Agency: NCI NIH HHS, United States
    Id: R01 CA148699
  • Agency: NCI NIH HHS, United States
    Id: R01 CA163722
  • Agency: NCATS NIH HHS, United States
    Id: UL1 TR000038

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