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Method to represent the distribution of QTL additive and dominance effects associated with quantitative traits in computer simulation.

BMC bioinformatics | 2016

Computer simulation is a resource which can be employed to identify optimal breeding strategies to effectively and efficiently achieve specific goals in developing improved cultivars. In some instances, it is crucial to assess in silico the options as well as the impact of various crossing schemes and breeding approaches on performance for traits of interest such as grain yield. For this, a means by which gene effects can be represented in the genome model is critical.

Pubmed ID: 26852240 RIS Download

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TASSEL (tool)

RRID:SCR_012837

Software package which performs a variety of genetic analyses including association mapping, diversity estimation and calculating linkage disequilibrium. The association analysis between genotypes and phenotypes can be performed by either a general linear model or a mixed linear model. The general linear model now allows users to analyze complex field designs, environmental interactions, and epistatic interactions. The mixed model is specially designed to handle polygenic effects at multiple levels of relatedness including pedigree information. These new analyses should permit association analysis in a wide range plant and animal species. (entry from Genetic Analysis Software)

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