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Population tailored modification of tuberculosis specific interferon-gamma release assay.

The Journal of infection | 2016

Blood-based Interferon-Gamma Release Assays (IGRA) identify Mycobacterium tuberculosis (MTB) sensitisation with increased specificity, but sensitivity remains impaired in human immunodeficiency virus (HIV) infected persons. The QuantiFERON-TB Gold In-Tube test contains peptide 38-55 of Rv2654c, based on data indicating differential recognition between tuberculosis patients and BCG vaccinated controls in Europe. We aimed to fine map the T cell response to Rv2654c with the view of improving sensitivity.

Pubmed ID: 26632326 RIS Download

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Associated grants

  • Agency: Wellcome Trust, United Kingdom
    Id: 081667
  • Agency: Wellcome Trust, United Kingdom
    Id: 104803
  • Agency: Medical Research Council, United Kingdom
    Id: U.1175.02.002.00014.01

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MatPlotLib (tool)

RRID:SCR_008624

Python 2D plotting library which produces publication quality figures in variety of hardcopy formats and interactive environments across platforms. Used in python scripts, web application servers, and six graphical user interface toolkits. Used to generate plots, histograms, power spectra, bar charts, error charts, scatter plots.

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