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Dexmedetomidine ameliorates acute lung injury following orthotopic autologous liver transplantation in rats probably by inhibiting Toll-like receptor 4-nuclear factor kappa B signaling.

Journal of translational medicine | 2015

To investigate whether pretreatment with dexmedetomidine (Dex) has a protective effect against acute lung injury (ALI) in an orthotopic autologous liver transplantation (OALT) rat model and to explore the mechanisms responsible for the protective effect of Dex against lung injury.

Pubmed ID: 26070954 RIS Download

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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