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Acute adaptive immune response correlates with late radiation-induced pulmonary fibrosis in mice.

Radiation oncology (London, England) | 2015

The lung response to radiation exposure can involve an immediate or early reaction to the radiation challenge, including cell death and an initial immune reaction, and can be followed by a tissue injury response, of pneumonitis or fibrosis, to this acute reaction. Herein, we aimed to determine whether markers of the initial immune response, measured within days of radiation exposure, are correlated with the lung tissue injury responses occurring weeks later.

Pubmed ID: 25889053 RIS Download

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Associated grants

  • Agency: Canadian Institutes of Health Research, Canada

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CRAN (tool)

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