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The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.

WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group | Martin A Adjuik | Richard Allan | Anupkumar R Anvikar | Elizabeth A Ashley | Mamadou S Ba | Hubert Barennes | Karen I Barnes | Quique Bassat | Elisabeth Baudin | Anders Björkman | François Bompart | Maryline Bonnet | Steffen Borrmann | Philippe Brasseur | Hasifa Bukirwa | Francesco Checchi | Michel Cot | Prabin Dahal | Umberto D'Alessandro | Philippe Deloron | Meghna Desai | Graciela Diap | Abdoulaye A Djimde | Grant Dorsey | Ogobara K Doumbo | Emmanuelle Espié | Jean-Francois Etard | Caterina I Fanello | Jean-François Faucher | Babacar Faye | Jennifer A Flegg | Oumar Gaye | Peter W Gething | Raquel González | Francesco Grandesso | Philippe J Guerin | Jean-Paul Guthmann | Sally Hamour | Armedy Ronny Hasugian | Simon I Hay | Georgina S Humphreys | Vincent Jullien | Elizabeth Juma | Moses R Kamya | Corine Karema | Jean R Kiechel | Peter G Kremsner | Sanjeev Krishna | Valérie Lameyre | Laminou M Ibrahim | Sue J Lee | Bertrand Lell | Andreas Mårtensson | Achille Massougbodji | Hervé Menan | Didier Ménard | Clara Menéndez | Martin Meremikwu | Clarissa Moreira | Carolyn Nabasumba | Michael Nambozi | Jean-Louis Ndiaye | Frederic Nikiema | Christian Nsanzabana | Francine Ntoumi | Bernhards R Ogutu | Piero Olliaro | Lyda Osorio | Jean-Bosco Ouédraogo | Louis K Penali | Mbaye Pene | Loretxu Pinoges | Patrice Piola | Ric N Price | Cally Roper | Philip J Rosenthal | Claude Emile Rwagacondo | Albert Same-Ekobo | Birgit Schramm | Amadou Seck | Bhawna Sharma | Carol Hopkins Sibley | Véronique Sinou | Sodiomon B Sirima | Jeffery J Smith | Frank Smithuis | Fabrice A Somé | Doudou Sow | Sarah G Staedke | Kasia Stepniewska | Todd D Swarthout | Khadime Sylla | Ambrose O Talisuna | Joel Tarning | Walter R J Taylor | Emmanuel A Temu | Julie I Thwing | Emiliana Tjitra | Roger C K Tine | Halidou Tinto | Michel T Vaillant | Neena Valecha | Ingrid Van den Broek | Nicholas J White | Adoke Yeka | Issaka Zongo
BMC medicine | 2015

Artesunate-amodiaquine (AS-AQ) is one of the most widely used artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium falciparum malaria in Africa. We investigated the impact of different dosing strategies on the efficacy of this combination for the treatment of falciparum malaria.

Pubmed ID: 25888957 RIS Download

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Associated grants

  • Agency: Wellcome Trust, United Kingdom
    Id: 091625
  • Agency: Wellcome Trust, United Kingdom
    Id: 093956
  • Agency: Wellcome Trust, United Kingdom
    Id: 095066
  • Agency: Medical Research Council, United Kingdom
    Id: MC_UP_A900_1119

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